ID A0A080LSW7_9PROT Unreviewed; 803 AA.
AC A0A080LSW7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Serine/threonine-protein kinase PrkC {ECO:0000313|EMBL:KFB70645.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:KFB70645.1};
GN Name=prkC_4 {ECO:0000313|EMBL:KFB70645.1};
GN ORFNames=AW09_004238 {ECO:0000313|EMBL:KFB70645.1};
OS Candidatus Accumulibacter phosphatis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=327160 {ECO:0000313|EMBL:KFB70645.1, ECO:0000313|Proteomes:UP000020077};
RN [1] {ECO:0000313|EMBL:KFB70645.1, ECO:0000313|Proteomes:UP000020077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BA-91 {ECO:0000313|Proteomes:UP000020077};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFB70645.1}.
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DR EMBL; JDVG02000668; KFB70645.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A080LSW7; -.
DR Proteomes; UP000020077; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR013976; HDOD.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR43671:SF13; LD04361P; 1.
DR PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR Pfam; PF08668; HDOD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51833; HDOD; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KFB70645.1};
KW Transferase {ECO:0000313|EMBL:KFB70645.1}.
FT DOMAIN 8..266
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 295..492
FT /note="HDOD"
FT /evidence="ECO:0000259|PROSITE:PS51833"
SQ SEQUENCE 803 AA; 88240 MW; 3C6F0CABA9539DAD CRC64;
MSKHVGRFEI IRELGRGAQS IVYLARDPHL QRQVAIKTLH FARSDPQQNR QLLDEARMVS
QLRHPNIVPI FEAAEERGDL YLVFQYVPGK NLAEHLAQSG APKPARAIAI MQAILDAIAH
AHAAGIIHRD LKPSNILIDD DELPRVMDFG IAARTGALSG DGGQLTGTPA YMAPEYILQR
TSSERSDIFS AGMVFYELLT GKRAIPGNDI LLVMKQIASE DIRLPQDSSG LLEERLAHLL
YRALARDPQS RYESARQMRE ALDDYLAPET LQPSADPRQS TIDFLLRRMR HKSDFPALSE
SVGAINRITA SENQSISEVS NTILKDFSLT NKLLRMVNSV YYQQAGGGNI STVSRAVVVL
GLDAVRSIAI TVLLLDHLQN KDNANQLKDE FLRANLAGVL ARDLAGKSAA RLDIEQAFIC
SMFHNLGRLL SQYYFPEESA EMKRMLLQKN CSEEAAALQV LGISLEDLGI GIAQTWGFPR
LIVNSMRRLP AGSIRRSLNP EDRLRVFSAL SNELCTVISE TASEQQAREL RKIAARFGEA
VALDEQELRS ALEKSLEQVT QFAATIHLNL QQTRFGRQIT AWGGAPTSPP TLELMPGTDD
GLAGTVLSDV IAEGVAADPV VDCGEFAAGT ETVASEAILL AGIQDLSNVL VNSFKLNDVL
RITLETIYRA KGFKRVILCI REARSNSMLG RFGFGPDALD IAKSFRFSLV FTPDIFHAAL
AKGVDILISD TNDPKIAARI PGWFRKAVAA ETFVVFPLCV NGNGVAMIYA DRAHAGEIVI
SEKELALMRT LRNMAVLAIK QSI
//
