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Database: UniProt
Entry: A0A081B730_9RHIZ
LinkDB: A0A081B730_9RHIZ
Original site: A0A081B730_9RHIZ 
ID   A0A081B730_9RHIZ        Unreviewed;       504 AA.
AC   A0A081B730;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=M2A_0347 {ECO:0000313|EMBL:GAK43848.1};
OS   Tepidicaulis marinus.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhodobiaceae; Tepidicaulis.
OX   NCBI_TaxID=1333998 {ECO:0000313|EMBL:GAK43848.1, ECO:0000313|Proteomes:UP000028702};
RN   [1] {ECO:0000313|EMBL:GAK43848.1, ECO:0000313|Proteomes:UP000028702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MA2 {ECO:0000313|EMBL:GAK43848.1,
RC   ECO:0000313|Proteomes:UP000028702};
RA   Takeuchi M., Yamagishi T., Kamagata Y., Oshima K., Hattori M.,
RA   Katayama T., Hanada S., Tamaki H., Marumo K., Maeda H., Nedachi M.,
RA   Iwasaki W., Suwa Y., Sakata S.;
RT   "Tepidicaulis marinum gen. nov., sp. nov., a novel marine bacterium
RT   denitrifying nitrate to nitrous oxide strictly under microaerobic
RT   conditions.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAK43848.1}.
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DR   EMBL; BBIO01000001; GAK43848.1; -; Genomic_DNA.
DR   EnsemblBacteria; GAK43848; GAK43848; M2A_0347.
DR   Proteomes; UP000028702; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028702};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028702}.
FT   DOMAIN      191    319       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      407    476       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     199    206       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   504 AA;  56137 MW;  CE269F8B912ED875 CRC64;
     MSGGSADRHD LKSQWDRVKA RLKAELGEAT YISWFQYADM IGVGDGKIVL SVPTRFIRSW
     LLAHQMDRLV GLWQDEDPTV QKIEILVRDP MRGDAPAPAS PASSAQAAAQ AAVQPSPAMR
     AAAAAARAGQ GQAAVQQTVY SGYASGPLGD GGEDLGAPLD PRFTFDNFVV GKSNELAHAA
     ARRVAETRDV SFNPLFLYGG VGLGKTHLMH AIAWEIRRKH PERKVLYLSA EKFMYQFIRA
     LRFKDTMAFK QQFRTVDVLM VDDVQFISGK ESTQEEFFHT FNALIDHNRQ VIISADRSPS
     DLEGIEERIR SRLGWGLVAD IHPTDYELRL GILQAKADEI MSSGGNIDIP PAVLEFLAHR
     IVSNVRELEG GLKRVVAYAS LVGRPISLEM AQDVLRDLLR SNERKVTIEE IQRRVAEYYN
     VRLADMLSAR RARAIARPRQ IAMYLSKQLT TRSLPEIGRK FGGRDHTTVI HAVRKVDSLC
     KEDAGLEEDV DLLRRMLEGG PPEL
//
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