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Database: UniProt
Entry: A0A081BHI0_9LACO
LinkDB: A0A081BHI0_9LACO
Original site: A0A081BHI0_9LACO 
ID   A0A081BHI0_9LACO        Unreviewed;       447 AA.
AC   A0A081BHI0;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   05-JUL-2017, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:GAK47498.1};
GN   ORFNames=LOSG293_070370 {ECO:0000313|EMBL:GAK47498.1};
OS   Lactobacillus oryzae JCM 18671.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=1291743 {ECO:0000313|EMBL:GAK47498.1, ECO:0000313|Proteomes:UP000028700};
RN   [1] {ECO:0000313|EMBL:GAK47498.1, ECO:0000313|Proteomes:UP000028700}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG293 {ECO:0000313|EMBL:GAK47498.1,
RC   ECO:0000313|Proteomes:UP000028700};
RA   Tanizawa Y., Fujisawa T., Mochizuki T., Kaminuma E., Nakamura Y.,
RA   Tohno M.;
RT   "Draft Genome Sequence of Lactobacillus oryzae Strain SG293T.";
RL   Genome Announc. 2:e00861-14(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAK47498.1}.
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DR   EMBL; BBJM01000007; GAK47498.1; -; Genomic_DNA.
DR   RefSeq; WP_034526848.1; NZ_BBJM01000007.1.
DR   EnsemblBacteria; GAK47498; GAK47498; LOSG293_070370.
DR   Proteomes; UP000028700; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028700};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028700}.
FT   DOMAIN      143    274       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      355    424       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     151    158       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   447 AA;  50484 MW;  CC038CA285928F9B CRC64;
     MLDLQSTWDA IAESFREIST PVTYSTWIAS AEPISLINRQ LTIKLPSALH RDYWENNLTQ
     ELVAFAYQAT HEDIQPDFII DSDLTEEKKS TTETTSDGPG LIPTFMKETK LNPKYTFDTF
     VIGKGNQMAH AAALVVSEEP GKMYNPLFFY GGVGLGKTHL MHAIGNKMMA DKPGTRVKYV
     TSEAFTNDFI NAIQTRTQEQ FRQEYRNADL LLVDDIQFFA DKEGTQEEFF HTFNSLYDDG
     KQIVLTSDRL PREIPKLQDR LVSRFAWGLS VDITPPDLET RIAILRNKAN ADQIDIPDDT
     LSYIAGQIDS NVRELEGALS RVHAYAKLKN TPISTDLVAK SLQSLNLGNA HTEITILAIQ
     NTVANYYHVS LADLKGKKRM KSIVMPRQIA MYLARELTDS SLPKIGNEFG GKDHTTVIHA
     YEKITESLKH DDNLKSELDD IKNELKR
//
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