ID   A0A081BQE5_9BACT        Unreviewed;       487 AA.
AC   A0A081BQE5;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Two-component hybrid sensor and regulator {ECO:0000313|EMBL:GAK52611.1};
GN   ORFNames=U14_03863 {ECO:0000313|EMBL:GAK52611.1};
OS   Candidatus Moduliflexus flocculans.
OC   Bacteria; Candidatus Moduliflexota; Candidatus Moduliflexia;
OC   Candidatus Moduliflexales; Candidatus Moduliflexaceae.
OX   NCBI_TaxID=1499966 {ECO:0000313|EMBL:GAK52611.1};
RN   [1] {ECO:0000313|EMBL:GAK52611.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sekiguchi Y., Ohashi A., Parks D.H., Yamauchi T., Tyson G.W.,
RA   Hugenholtz P.;
RT   "First genomic representation of candidate bacterial phylum KSB3 points to
RT   enhanced environmental sensing as a trigger of wastewater bulking.";
RL   PeerJ 3:e740-e740(2015).
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DR   EMBL; DF820458; GAK52611.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A081BQE5; -.
DR   STRING; 1499966.U14_03863; -.
DR   HOGENOM; CLU_559809_0_0_0; -.
DR   Proteomes; UP000030700; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030700};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          212..264
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
SQ   SEQUENCE   487 AA;  54149 MW;  D7663F9C69BD8CEC CRC64;
     MYIRNMKIGT RLIVFIGGVL LLLSISNIIL LIFLSTHLFS LTERLYKHPF TVNKTVRDAH
     LSVLNIRLAM KDAITEQDRD KLEALIADVR KEEESIVNDF AVIKERYLGD PKDVQTVIDV
     FAAWKKERDA MIELLRKNQR EEAAKSINTG STNEQYLAMK NALAVLTEFS GNKALSFLKN
     AEVAKRDETL VAMAISIGGF FISLSILAVI ARTITRPLNS VVVIADRVSE GNLDVDFPPA
     SHDEVGQVLQ SMRNMVAYLR QVAAVADQVA RQELHAEVHP KSAHDVLNLA LERMLINLRQ
     MVTEIERSLK AVEEQNWLKD GVSQLSQSLV GDMSLDNVCQ KALQELARYL NAGHGVLYVY
     DADHHVLQLR GTFAFTEADE LRQEVRLGEG IIGQAARERA PITLTNAPHQ HGQINTGTSS
     EPPLTIYAMP ATYNNELYGV IELATGEALS PLHEAFLASA NNVIAMAIFS ALQRERVHAL
     LQQSQIA
//