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Database: UniProt
Entry: A0A081MCL5_9RHIZ
LinkDB: A0A081MCL5_9RHIZ
Original site: A0A081MCL5_9RHIZ 
ID   A0A081MCL5_9RHIZ        Unreviewed;       488 AA.
AC   A0A081MCL5;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=GV67_11975 {ECO:0000313|EMBL:KEQ03938.1};
OS   Pseudorhizobium pelagicum.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Pseudorhizobium.
OX   NCBI_TaxID=1509405 {ECO:0000313|EMBL:KEQ03938.1, ECO:0000313|Proteomes:UP000052187};
RN   [1] {ECO:0000313|EMBL:KEQ03938.1, ECO:0000313|Proteomes:UP000052187}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R1-200B4 {ECO:0000313|Proteomes:UP000052187};
RA   Kimes N.E., Lopez-Perez M.;
RT   "Rhizobium pelagicum/R1-200B2.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KEQ03938.1}.
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DR   EMBL; JOKI01000022; KEQ03938.1; -; Genomic_DNA.
DR   EnsemblBacteria; KEQ03938; KEQ03938; GV67_11975.
DR   Proteomes; UP000052187; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000052187};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052187}.
FT   DOMAIN      178    306       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      393    462       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     186    193       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   488 AA;  54477 MW;  3C3259072F3E39F2 CRC64;
     MKHEALFERF SKRLKAQVGQ DVYASWFGRL KLHSISKSVV RLTVPTTFLK SWINNRYLDQ
     ITTILQAEDP DILKVEILVR SASRSARPVA SEDRPLIAEA APSAAAPMSF PRGSAARETG
     KVASFPMSLG TRPAAAGPLF GSPLDSRFTF DSYIEGPSNR VALAAAKTIA EAGAGAVRFN
     PLFIHSGVGL GKTHLLQAIA NSAVSSARAP RVVYLTAEYF MWRFATAIRD NDALTLKDSL
     RNIDLLIIDD MQFLQGKMIQ NEFCHLLNTL LDSAKQVVVA GDRAPWELES LDPRVRSRLQ
     GGVAIEMESP DYEMRFEMLK RRLEIAQQDD PSLDISVEIL SHVARSVASS GRDLEGAFNQ
     LVFRKSFEPS LSLERVDELL VHLVGTGEAK RVRIEDIQRI VARHYNVSRQ ELVSNRRTRV
     VVKPRQIAMY LAKTLTPRSF PEIGRRFGGR DHTTVLHAVR KIEDLITGDT KLCHEVELLK
     RLINENNA
//
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