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Database: UniProt
Entry: A0A081NDS0_9GAMM
LinkDB: A0A081NDS0_9GAMM
Original site: A0A081NDS0_9GAMM 
ID   A0A081NDS0_9GAMM        Unreviewed;       520 AA.
AC   A0A081NDS0;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   05-JUL-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=GZ78_22450 {ECO:0000313|EMBL:KEQ16593.1};
OS   Endozoicomonas numazuensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae; Endozoicomonas.
OX   NCBI_TaxID=1137799 {ECO:0000313|EMBL:KEQ16593.1, ECO:0000313|Proteomes:UP000028073};
RN   [1] {ECO:0000313|EMBL:KEQ16593.1, ECO:0000313|Proteomes:UP000028073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25634 {ECO:0000313|EMBL:KEQ16593.1,
RC   ECO:0000313|Proteomes:UP000028073};
RA   Neave M.J., Apprill A., Voolstra C.R.;
RT   "Whole Genome Sequences of Three Symbiotic Endozoicomonas Bacteria.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KEQ16593.1}.
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DR   EMBL; JOKH01000005; KEQ16593.1; -; Genomic_DNA.
DR   RefSeq; WP_034840265.1; NZ_JOKH01000005.1.
DR   EnsemblBacteria; KEQ16593; KEQ16593; GZ78_22450.
DR   Proteomes; UP000028073; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028073};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028073}.
FT   DOMAIN      217    425       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      428    497       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     225    232       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   520 AA;  58438 MW;  96811CF1E16814FE CRC64;
     MPLELWQKCV DLLQDELSSQ QFNTWIRPLK VMGDEHDLCL LAPNRFVADW VKEKFLPRVE
     EILDELTDGQ SPAVALAVSN RRPQSLSRRV SAPVSRPVRT ETAKPAGEEE KVVTGLVSSL
     SQAAGSSSSH HEPSRMVEPP VLQKKVNPLK VKEDTVSSHQ PVEKEKPSAG RQIEVEGSIK
     HNSSLNAHFT FDTFVEGKSN QLALAAARQV AENPGAAYNP LFLYGGVGLG KTHLMHAVGN
     SLVRQNRNAR VVYLHSERFV ADMVKALQLN AINDFKRYYR SVDALLIDDI QFFAGKERSQ
     EEFFHTFNAL LEGGQQMILT CDRYPKEING VEERLKSRFG WGLTVAVEPP ELETRVAILM
     KKAEQQKVDL PHEAAFFIAQ RIRSNVRELE GALKRVIASA HFMGRKIDID LIRESLKDLL
     ALQDKQVSID NIQRTVAEYY KIKVADILSK RRSRSVARPR QIAMALSKEL TSHSLPEIGD
     AYGGRDHTTV LHACRKVKEL VGEDGEIRDD YKNLLRSLTS
//
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