ID   A0A081P9X4_9BACL        Unreviewed;       416 AA.
AC   A0A081P9X4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Zinc protease {ECO:0000313|EMBL:KEQ27497.1};
GN   ORFNames=ET33_19840 {ECO:0000313|EMBL:KEQ27497.1};
OS   Paenibacillus tyrfis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1501230 {ECO:0000313|EMBL:KEQ27497.1, ECO:0000313|Proteomes:UP000028123};
RN   [1] {ECO:0000313|EMBL:KEQ27497.1, ECO:0000313|Proteomes:UP000028123}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSt1 {ECO:0000313|EMBL:KEQ27497.1,
RC   ECO:0000313|Proteomes:UP000028123};
RA   Aw Y.K., Ong K.S., Gan H.M., Lee S.M.;
RT   "Draft genome sequence of Paenibacillus sp. MSt1.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEQ27497.1}.
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DR   EMBL; JNVM01000003; KEQ27497.1; -; Genomic_DNA.
DR   RefSeq; WP_036676331.1; NZ_JNVM01000003.1.
DR   AlphaFoldDB; A0A081P9X4; -.
DR   MEROPS; M16.A15; -.
DR   eggNOG; COG0612; Bacteria.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000028123; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:KEQ27497.1};
KW   Protease {ECO:0000313|EMBL:KEQ27497.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028123}.
FT   DOMAIN          12..158
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          165..337
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   416 AA;  46325 MW;  AF84E1817BFFD133 CRC64;
     MDKYTLTNGL RLVIEKIPTC RSVAFGIWVK TGSRSENETN NGISHFIEHM LFKGTEKYSA
     KDIAEIFDGI GGNVNAFTSK EYTCYYCKVL DEHLPLAVEV LSDMFFGSVF DGTELEKEKN
     VIYEEIAMYE DTPDDMVHDL IARAAFGGHS LGRTIIGTQS NLAAMTSDTL KEYMKSHYTI
     ANTVISIAGN INDDVVGLIE KHFGSFANVG SQAPLEPLTF RSDSEYHQKK TEQNHICLSL
     PGLAAKDDRL YAMILLNNAI GGGMSSRLFQ EIREKRGLAY SVYSYHSSYQ DGGLFTVYTG
     TAPKQTEEVL KVTLELLADI KEKGLTPTEL KKGKEQMKGS LILSLESTSS RMNRIGKNEL
     MLGRHYNLDE MIQRIESVEM EHVQALTAEL LSVPFALAMV GQTNEAIAGF RRDQLV
//