ID A0A084JIP6_9CLOT Unreviewed; 606 AA.
AC A0A084JIP6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Flagellar biosynthetic protein FliR {ECO:0000256|RuleBase:RU362071};
GN ORFNames=IO99_01325 {ECO:0000313|EMBL:KEZ88830.1};
OS Clostridium sulfidigenes.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=318464 {ECO:0000313|EMBL:KEZ88830.1, ECO:0000313|Proteomes:UP000028542};
RN [1] {ECO:0000313|EMBL:KEZ88830.1, ECO:0000313|Proteomes:UP000028542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=113A {ECO:0000313|EMBL:KEZ88830.1,
RC ECO:0000313|Proteomes:UP000028542};
RA Honkalas V.S., Dabir A.P., Arora P., Dhakephalkar P.K.;
RT "Draft genome of Clostridium sulfidigenes 113A isolated from sediments
RT associated with methane hydrate from Krishna Godavari basin.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Role in flagellar biosynthesis.
CC {ECO:0000256|ARBA:ARBA00002578, ECO:0000256|RuleBase:RU362071}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362071};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362071}. Bacterial
CC flagellum basal body {ECO:0000256|RuleBase:RU362071}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family.
CC {ECO:0000256|ARBA:ARBA00009772, ECO:0000256|RuleBase:RU362071}.
CC -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC {ECO:0000256|ARBA:ARBA00010690}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEZ88830.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPMD01000001; KEZ88830.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084JIP6; -.
DR STRING; 318464.IO99_01325; -.
DR eggNOG; COG1377; Bacteria.
DR eggNOG; COG1684; Bacteria.
DR Proteomes; UP000028542; Unassembled WGS sequence.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.2080; -; 1.
DR Gene3D; 3.40.1690.10; secretion proteins EscU; 1.
DR InterPro; IPR006136; FlhB.
DR InterPro; IPR006303; FliR.
DR InterPro; IPR002010; T3SS_IM_R.
DR InterPro; IPR006135; T3SS_substrate_exporter.
DR InterPro; IPR029025; T3SS_substrate_exporter_C.
DR NCBIfam; TIGR00328; flhB; 1.
DR NCBIfam; TIGR01400; fliR; 1.
DR PANTHER; PTHR30531; FLAGELLAR BIOSYNTHETIC PROTEIN FLHB; 1.
DR PANTHER; PTHR30531:SF12; FLAGELLAR BIOSYNTHETIC PROTEIN FLHB; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR Pfam; PF01312; Bac_export_2; 1.
DR PRINTS; PR00950; TYPE3IMSPROT.
DR SUPFAM; SSF160544; EscU C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|RuleBase:RU362071};
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Bacterial flagellum protein export {ECO:0000256|ARBA:ARBA00023225};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362071};
KW Cell projection {ECO:0000313|EMBL:KEZ88830.1};
KW Cilium {ECO:0000313|EMBL:KEZ88830.1};
KW Flagellum {ECO:0000313|EMBL:KEZ88830.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362071};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000028542};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362071};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362071}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 5..23
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 119..142
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 162..192
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 213..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 346..371
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 392..415
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 440..465
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
SQ SEQUENCE 606 AA; 67276 MW; 21585A6142B78C92 CRC64;
MFIAFLMVFM RITSLIFTVP TFFPTGTPNI AKIGVGLIIS MILSPIVSTE ALPEISNIFV
FIVLIGKEVV IGICLGYIVN LLFSVVQMAG QIMDFSMGFS MMSLFDPVAG ENISVMGRLM
YWICLAVFML VDGHLILVQC LIDSFTSVPV GTVTFNKEIL GYIIQVVFEF FTIGIKIAVP
IMLIILMTEI VLGLVSRVMP QLNAMILGMP IKIFVGLATF VISIPLIMKI IASNFGAIKH
IFSEIFTMMP FILISASNDS GDKTEKPTPK KLQDAKKKGQ VAKSKELSSA LTLLAATLVI
AILSSFVLKV LSSSMTKYLG SYLNFQLSQE SLVGLLIKVF MDIFKIFIPV AVPIMVIGVI
GSIIQTGFIY TGDPLKPKFS KLNPISGFKR MFSIRSLVDL VKNLGIVSIV GYIGYKFVID
NYYSLLNFGN LKTGSILTEL ASLIINVFVK VGIALLIIGC IDFLYQKFQH NKDLKMTKQE
IKEEYKQQEG DPIVKGKRKQ KQREMAMRRM MQSVPDATVV ITNPTHIAVA LKYEENSGKA
PIVVAKGSEY VALKIKEKAI ENNVPIIENK PLARLMFKEV DLDKEIPFDM YKAVAEILVL
VYKMKK
//
