ID A0A084W0J7_ANOSI Unreviewed; 919 AA.
AC A0A084W0J7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=AGAP001146-PA-like protein {ECO:0000313|EMBL:KFB43741.1};
DE SubName: Full=WD_REPEATS_REGION domain-containing protein {ECO:0000313|EnsemblMetazoa:ASIC011476-PA};
GN ORFNames=ZHAS_00011476 {ECO:0000313|EMBL:KFB43741.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB43741.1};
RN [1] {ECO:0000313|EMBL:KFB43741.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC011476-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat WDR3/UTP12 family.
CC {ECO:0000256|ARBA:ARBA00038229}.
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DR EMBL; ATLV01019122; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525262; KFB43741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084W0J7; -.
DR STRING; 74873.A0A084W0J7; -.
DR EnsemblMetazoa; ASIC011476-RA; ASIC011476-PA; ASIC011476.
DR VEuPathDB; VectorBase:ASIC011476; -.
DR VEuPathDB; VectorBase:ASIS003542; -.
DR OMA; MQCLRTV; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProt.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19853; WD REPEAT CONTAINING PROTEIN 3 WDR3; 1.
DR PANTHER; PTHR19853:SF0; WD REPEAT-CONTAINING PROTEIN 3; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 8.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 60..120
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 150..192
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 395..435
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 477..511
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 573..614
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 615..656
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 657..688
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 776..879
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
SQ SEQUENCE 919 AA; 102457 MW; 798CAB30F117DEBE CRC64;
MTQGKMGLTK QYLAYKPVSS FNIIASSRAN ISFISVNNVD GRYVVVAAAE KVIVWNMRIG
EKVAEFTRDK QEVTFLRASP DHKHLAVGYA DGVVEMFSFE SKQSVCSFAA HRSAVSALNF
DLLGLKLASG GLDNDVVVSD VVAQTGKCRL TGHSAPITQV CFMQRYHDVI VTSSKDTQIK
FWNVETHCCF KTIVDHRTEV WGIVLMRNDD FLVCGSADTQ LSVYRIAPNT EESKPIQATE
EQLLVEESTV SPFRCTAIGS IQRAGHGRTI NLVADGNGQV LGCHGTDKKI ELFYFAPVDE
AVKKLTKRMK KLNTKKSTDT ETQTEVDVRQ LSLTDEIKRL SPILTSDKVK SFDLLLGSRS
ELRICCTFVK NFIELFSLDM DVKKAEPVSL HSIHKQGHPS EARSVSFSSD NLAIASGSAE
SLKLWNRSSQ TVLRTIDTSG YVVSTCFVPG DRHVLVGLKS GELLIVDIVA GDELERIEAH
EKEIWSIVLT PDMHGCVTGG GDMTVKFWSF ELIANPERPD LKVLSLLHKN TLKLEETVLC
VKISANGKYI AVALLDTTVK IFFLDSHKFY LSLYGHKLPV LTMDISYDSS LIVTGSADRT
IKIWGMDFGD CHRSLLAHDN TVTALQFIPN THMFFSCGKD GKLKQWDADN FQKIVTLPGH
LGEAHALAIS PNGKYVVSCG SDRTLRLFHR TDEPLVLQDV QEEEREELEN ATLATGEESA
VPGLPGLQLP SKKTIGSEKG AENILECLEV SKQYEQEGAK GPLPPLMFAY SATNTDDFLL
TVLSRIRASD LEESLLLLPF SAVCELLERI PKLTITRKDQ TELICKVVLF LFRVHQKPIV
SNQVLLPVIQ KIIHTLQEAI CELRDMIGMN FHASQMLQRE LEENDGCVLF RDATKLRVQR
DRRRKRREAS KRTLVNITK
//
