ID A0A084W6V4_ANOSI Unreviewed; 446 AA.
AC A0A084W6V4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN ORFNames=ZHAS_00013914 {ECO:0000313|EMBL:KFB45948.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB45948.1};
RN [1] {ECO:0000313|EMBL:KFB45948.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC013914-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|RuleBase:RU361177};
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC ECO:0000256|RuleBase:RU361177}.
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DR EMBL; ATLV01020961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525310; KFB45948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084W6V4; -.
DR STRING; 74873.A0A084W6V4; -.
DR EnsemblMetazoa; ASIC013914-RA; ASIC013914-PA; ASIC013914.
DR VEuPathDB; VectorBase:ASIC013914; -.
DR VEuPathDB; VectorBase:ASIS008732; -.
DR OMA; DDWEVYV; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF266; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR PIRSF; PIRSF000332; FMO; 2.
DR PRINTS; PR00370; FMOXYGENASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU361177};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU361177}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU361177};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765}.
SQ SEQUENCE 446 AA; 51205 MW; 7FBCA45F06B288BF CRC64;
MPCEHFQQKR YCIIGAGASG ICSAKTALDA GGHVTLYERT DRIGGTWVYT EDVGTDRYGL
PVHSSMYDGL KTNLPKEIMG FPGYEMPEQD VSYVRSDEVL QFLQDYSDYY NVTERIHFAH
LVEEVKPATD GSNGWTVRVR NLTDESIDTQ SFDFVLICNG HYHTPHIPSY DGREHFRGMQ
LHSHDYRKPD VFRGQTVLVI GAGPSGTDLT LEAAKQAKTV YFSHHVPEKL KHLVFPANVI
QVPDVLRIHP DSVEFQDGTN HQITVIFYCT GYRYSFPFLH PDCGVEVDDN WVRPLYKHVL
NINHSTMAFI GLPFYVCATL MFELQARFCV AFYSGRLPMP KKTEMIDDHE CEMNERWSRG
LKKRQAHMMG ADYQGSYYRS LAQRAQITPI PEVMTDIHID SGKRKKEDLQ NYRNDVYRIV
DDKTYVKCHI SELNNLMENL AVKKSS
//
