ID A0A084WR18_ANOSI Unreviewed; 514 AA.
AC A0A084WR18;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=AGAP003718-PA-like protein {ECO:0000313|EMBL:KFB52662.1};
GN ORFNames=ZHAS_00020916 {ECO:0000313|EMBL:KFB52662.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB52662.1};
RN [1] {ECO:0000313|EMBL:KFB52662.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC020916-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ATLV01025888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525402; KFB52662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084WR18; -.
DR STRING; 74873.A0A084WR18; -.
DR EnsemblMetazoa; ASIC020916-RA; ASIC020916-PA; ASIC020916.
DR VEuPathDB; VectorBase:ASIC020916; -.
DR VEuPathDB; VectorBase:ASIS005748; -.
DR OMA; CACRMVP; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08705; RGS_R7-like; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR034483; RGS_Egl-10.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF6; LP21163P; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 94..169
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 375..494
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 20..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 58025 MW; 3449C4D40ADFC6BB CRC64;
MVTKKSVDIE KEKLAKNMYS SSSSAGTGIP AKASGTGAGS GSSGTAVVSF SAGTMANSGS
SHMAQQILPH GGQDAPNILV YKKMEAIVER MQTEGTGVSV RTVKAFMSKV PSVFTGADLI
QWIMANLTVD DISEALHLAH LLASHGYLFP IDDHQLTVRN DGTFYRFQTP YFWPSNFWEP
ENTDYAIYLC KRTMQNKTRL ELADYEAENL AKLQKMFSRK WEFIFMQAEA QSKVDKKRDK
LERKVLDSQE RAFWDVHRPM PGCVNTTEMD IKKAYRKGAS SLGSGSAGTA AHSNPAETMA
KTITLLKQKL DRRTIKVSKV AESYISYYEQ YSEFDYFLSA PDHPNPWHTD NTEFWDAEKL
GKDIPMKRVK RWGFSLRELL NDPVGREQFT KFLDKEFSGE NLKFWEAIQD MKALPQSQIK
DAAKAIWNEY LAPDAACPVN IDSKSLELAR EVVKEGAAQP SRWCFDVAAD HVFYLMKSDS
YSRFLRSDMY KECLNGSKKK VKSIPNLFGV KLNY
//
