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Database: UniProt
Entry: A0A085FBK1_9RHIZ
LinkDB: A0A085FBK1_9RHIZ
Original site: A0A085FBK1_9RHIZ 
ID   A0A085FBK1_9RHIZ        Unreviewed;       512 AA.
AC   A0A085FBK1;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   05-JUL-2017, entry version 22.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA_1 {ECO:0000313|EMBL:KFC68846.1};
GN   Synonyms=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=FF80_01801 {ECO:0000313|EMBL:KFC68846.1};
OS   Devosia sp. LC5.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Hyphomicrobiaceae; Devosia.
OX   NCBI_TaxID=1502724 {ECO:0000313|EMBL:KFC68846.1, ECO:0000313|Proteomes:UP000028638};
RN   [1] {ECO:0000313|EMBL:KFC68846.1, ECO:0000313|Proteomes:UP000028638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LC5 {ECO:0000313|EMBL:KFC68846.1,
RC   ECO:0000313|Proteomes:UP000028638};
RA   Gan H.M., Gan H.Y., Barton H.A., Savka M.A.;
RT   "Genome sequence of acyl-homoserine lactone-producing cave bacterial
RT   isolate.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFC68846.1}.
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DR   EMBL; JNNO01000012; KFC68846.1; -; Genomic_DNA.
DR   EnsemblBacteria; KFC68846; KFC68846; FF80_01801.
DR   PATRIC; fig|1502724.3.peg.1793; -.
DR   Proteomes; UP000028638; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028638};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028638}.
FT   DOMAIN      206    328       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      420    489       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     214    221       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   512 AA;  56409 MW;  FBF586EE948A0D56 CRC64;
     MMMQTAGKDD WGNPQPSSTT PTLKGEMSVM ITSGSEAQRD LFNRVRARLK AAVGEDVFTS
     WFARLELEEI VDDLVHLSAP TRFLCSWVQS NYADRIIESF RQDVDSVTRL QVTLRVNGQA
     TKKLAPAAEI APSGDAGAPA SVAAAPQAPA TPRLVRDNSA SKGDALAGSA IDQRMTFETF
     VPGAANEMAF GVAKQIAHAA ANNSVTFNPV YIHSTVGLGK SHLLNAIAHA VQSADASKNI
     VYLTADHFMY HFITAVQRQS ALGFKEWLRR VDLLLIDDMQ FLQGKSATEF GHTLGTLLTG
     AKQVVVAGDA PPRDLEMIDE RIRSRLSGGL VVPITGFDME LRRAIVQRRA DQASARYGMH
     FPTPVIDYVS RAVVSHGRDL DGAVNRLVAA NQLTGELITV PLAEKTLADL IRARDAKRVR
     IEDILRIVSR HYKVPRNELL SARRSRDVVR PRQIAMFLAK ALTSRSLPEI GRRFGGRDHT
     TVLHSVRKVE SMMKDDIELC QEIELLKRML EE
//
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