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Database: UniProt
Entry: A0A085FHB5_9BRAD
LinkDB: A0A085FHB5_9BRAD
Original site: A0A085FHB5_9BRAD 
ID   A0A085FHB5_9BRAD        Unreviewed;       500 AA.
AC   A0A085FHB5;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KFC70860.1};
GN   ORFNames=FG93_02617 {ECO:0000313|EMBL:KFC70860.1};
OS   Bosea sp. LC85.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bosea.
OX   NCBI_TaxID=1502851 {ECO:0000313|EMBL:KFC70860.1, ECO:0000313|Proteomes:UP000028622};
RN   [1] {ECO:0000313|EMBL:KFC70860.1, ECO:0000313|Proteomes:UP000028622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LC85 {ECO:0000313|EMBL:KFC70860.1,
RC   ECO:0000313|Proteomes:UP000028622};
RA   Gan H.M., Gan H.Y., Barton H.A., Savka M.A.;
RT   "Genome sequence of acyl-homoserine lactone-producing cave bacterial
RT   isolate.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFC70860.1}.
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DR   EMBL; JPKG01000027; KFC70860.1; -; Genomic_DNA.
DR   EnsemblBacteria; KFC70860; KFC70860; FG93_02617.
DR   PATRIC; fig|1502851.3.peg.2642; -.
DR   Proteomes; UP000028622; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028622};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028622}.
FT   DOMAIN      194    323       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      408    477       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     202    209       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   500 AA;  54455 MW;  2FB66C277F2801C5 CRC64;
     MDEITEAKAV PASVIATTTA SIQGEGAALS LAEAWDRVRR RLRAELGEDV FSSWFARVEI
     GGLVDGVAYL TVPTRFLKSW LEAHYAERLR AHCLAELPAA NGILLSVRQA ARDSIPAAVR
     EAAMAAPRAA APVPVTAARS AETGALPCEQ ELVDACGTML DRRLNFQSFI VGKSNQLAFA
     AAERIAAAPA GTTPYNPLYL HAGVGLGKTH LLQAIAQDAR NHGKRVAYFT ADRFMYGFVA
     ALKSQTALAF KEKLRGIDLL IVDDVQFIQG RSIQQEFGHT INALIDAGKQ IVVAADRLAN
     DLEALDERIR SRLAGGLVVE VGELDEALRV KILGSRLESL QAAHSSFHVN SDVIAYVARV
     ITTNGRDLDG AANRLLAHAT LSGNAVTLET AEAAIRDLVR TREPRRVKIE DIQKLVATRY
     NVSRADILSE RRTAAVVKPR QIAMYLSKAL TPRSLPEIGR RFGGRDHTTV LHAVRKIEKA
     IAEDRLLHDE VDLLKRMLQE
//
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