ID A0A085LDI8_9MICO Unreviewed; 347 AA.
AC A0A085LDI8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Hemolysin {ECO:0008006|Google:ProtNLM};
GN ORFNames=IU11_15245 {ECO:0000313|EMBL:KFD43034.1};
OS Cellulosimicrobium sp. MM.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Cellulosimicrobium.
OX NCBI_TaxID=1523621 {ECO:0000313|EMBL:KFD43034.1, ECO:0000313|Proteomes:UP000028634};
RN [1] {ECO:0000313|EMBL:KFD43034.1, ECO:0000313|Proteomes:UP000028634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM {ECO:0000313|EMBL:KFD43034.1,
RC ECO:0000313|Proteomes:UP000028634};
RA Lal R., Sharma A., Sangwan N., Hira P.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KFD43034.1, ECO:0000313|Proteomes:UP000028634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM {ECO:0000313|EMBL:KFD43034.1,
RC ECO:0000313|Proteomes:UP000028634};
RA Khurana J.P.;
RT "Draft genome sequence of Cellulosimicrobium sp. MM isolated from arsenic
RT rich microbial mats of a himalayan hotspring.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFD43034.1}.
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DR EMBL; JPQW01000224; KFD43034.1; -; Genomic_DNA.
DR RefSeq; WP_034655108.1; NZ_JPQW01000224.1.
DR AlphaFoldDB; A0A085LDI8; -.
DR GeneID; 66332881; -.
DR Proteomes; UP000028634; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR43099:SF5; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000028634};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..202
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 220..280
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 347 AA; 36778 MW; CF68F2B985009962 CRC64;
MSSTTALLVA LLLLAGNAFF VGAEFAVISA RRSAIEPLAA QGNRRAQTVL WAMEHVSLML
ACAQLGVTVC STGLGVVAEP AIAHLIEDPL HALGVSTALA HPIAFVVALA IVVYLHVVLG
EMVPKNLAVS GPETAVMWFG PPLVWIGRVL RPVIVALNWL ANHAVRATGV EPKDEVASAF
TAEEVQSIVE HSQAEGVLRD EQGLLSGAIE FSERTAQDVM VPVADLVTVT EGCTPDEVER
LVAKTGFSRF AVADVTGDLV GYLHVKDVLY ADETTREAPV PSWRVRALAA AAPDDEVEDA
LRAMQRSGAH LARVDGPEGG GALGVVFLED ILEELVGEVR DAMQRRP
//
