ID A0A085MQQ8_9BILA Unreviewed; 992 AA.
AC A0A085MQQ8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Reverse transcriptase {ECO:0008006|Google:ProtNLM};
GN ORFNames=M514_28268 {ECO:0000313|EMBL:KFD59554.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD59554.1};
RN [1] {ECO:0000313|EMBL:KFD59554.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD59554.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
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DR EMBL; KL367837; KFD59554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085MQQ8; -.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
FT DOMAIN 160..339
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 693..855
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 992 AA; 111874 MW; 02EE248694ABF1C9 CRC64;
MVSHQFLVAD QLIVDVIIGT DFLAAHHVSI DVANNRAFGP TTGELTTNVI VSTAQPNYAS
LTQPLPATCG SRAIESQTDP LEYCSVPRYR TDNAAVELPR HPPLYSGLIS SYSHLFKLVP
GSTSVAEHQI RTSGTPVRVP PRRIPERYRA EVVSQLQEML DRGIIEPSQS PWMAPAVYTT
KRSGEVRICV DYRELNKRTL KDAYPLPMPD DIFEKVASAS VFSTLDMHCG FWQIPVRKDD
IEKTAFSPGP GMGLYQFKRM PFGLCGAPNT FQRVMDGLLR DLPFVVVYLD DIIVFSPDET
THHEHLRVVL ERLSAAGFTL RGAKCKIGLT EVRYLGHVIS GKSIAPDPAK VAAIESWPTP
TNRKTVKQFL GLTSYYRCFV KDYATIATPL YKLLHEDTPF KWTDTCEDAF NRLRRHLSSA
PVLVPPKFDR HFELFTDASN DGLGATLQQD GHAIAFASRT LTNSERNYSV IERECLAIVF
ALKTFRHYLL GRHFTIFTDH APLQWLTAQK MEGRLARWAL ALQEYDYTIK YRPGHKNNSA
DALSRRSGLA ATVLVLPELT RERIRQEQQS DAVLRGITEA LTNGIPIHSN PDVPRRYRQV
RRQLCLVDGI LMRTLKPRYA AEPVTVIIAP PSLRTYFLQA AHDIPSSGHQ GTAKTLGKLT
MLAYWPSMAE DVKRYCANCN ICQQVKPSPL PPAPLQPFPF GKPWERVAVD ILEVPMSQLG
NRYLLVLQDW FTKWVEAVPM KNQMAATISS VLVEIFSRMG IPDILHTDQG ANFESNLLRS
VLKAFGVQKT RTSAYHPQGD GLVERANRSI LQMLRTYVDS EADWKPHLAL VLHAYRTVPH
SSTGVAPFTL MYGRQAKLLP STPVITPEWY HSTNSWISAL PTTLSRLYSF AREHMRKVRE
QQKTQYDKRT APRNELTVGT PVWLWYPRKG KLQPKWQPGW TVVQIISPNT VKITKESGEE
SVVHVNRIRA RNIRSNGPRS IDITNAEDTS SI
//
