ID A0A085MX43_9BILA Unreviewed; 840 AA.
AC A0A085MX43;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 2 {ECO:0000256|ARBA:ARBA00020977};
DE AltName: Full=Component of oligomeric Golgi complex 2 {ECO:0000256|ARBA:ARBA00031344};
DE Flags: Fragment;
GN ORFNames=M514_04322 {ECO:0000313|EMBL:KFD61789.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD61789.1};
RN [1] {ECO:0000313|EMBL:KFD61789.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD61789.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the COG2 family.
CC {ECO:0000256|ARBA:ARBA00007603}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000256|ARBA:ARBA00006824}.
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DR EMBL; KL367611; KFD61789.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085MX43; -.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007030; P:Golgi organization; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR009316; COG2.
DR InterPro; IPR024603; COG_complex_COG2_C.
DR InterPro; IPR024602; COG_su2_N.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR12961; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2; 1.
DR PANTHER; PTHR12961:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2; 1.
DR Pfam; PF06148; COG2; 1.
DR Pfam; PF12022; COG2_C; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 195..323
FT /note="Conserved oligomeric Golgi complex subunit 2 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06148"
FT DOMAIN 525..805
FT /note="COG complex component COG2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12022"
FT NON_TER 840
FT /evidence="ECO:0000313|EMBL:KFD61789.1"
SQ SEQUENCE 840 AA; 95659 MW; A7D3A82F5BE26B3E CRC64;
MQALRNIGAL KAKCTEMYAW YNRKLLLHPW KGQMVVAGFM MISGDLISQI AVERRRSLNE
IEVERAARFL FIGTFYVGPS LWAWFTFLER RFPGTTIGVA VKRMMLDQLV FAPVSYLGFL
ALIGFLKSMD SDGVREKVEN EFWPVYLANL KVWPAVQLFN FYIIPVQHRL LITKCVGFLW
NAFLSAMHDE ATSFCFDRSK FTHSAFNAHQ LLRGAMELGF SLERIRDDLR VYLKIIQNSM
IEMINQDYAH FVLLSSNIVN LRSPVDKLVQ SVEKAANEID QSDTRLKASE LTEKLEEQRR
LSSNAQQLQS KLITMQLLQR IKNLLQSPNP DNFVLSALAR HILKAKVVVE LSDEKSNRDT
LNRCLAQIGE YLQAEFGPSF LVSIRNEDHN RIGKLLELFT ACGCDDALHA VFIAEFVNPR
LNECLLKREV PFKAVLSELT VIHKEYFSLL SKAAKSSGVT FLADCLLMAL VGFTERHLKS
SFVPTDPSNF RDTYRAFSNF AAELVRRCGS VEASTSKLLK LTRSKFDVQV YHQLCCLETL
SSLEEIMKPS VPLEPSTGSA YHFKLHDLLC NTLERIWCEE QSINGLFLLP LAWSCLILTF
RLLNVYEKFV GEYHRNCESL LDELDFAANK PSKQNVEDVV HFIKDGFRFV DFLSKIYDRL
LLPKWSSDFS TSRVHEVVKS SLSSIELVIS GLVSSLLTDW LSSRLIRYWA AVSDLPRLFR
WTRKESPIKI HQLLSDASVP NDLLRDMFRR TLDTATSIYA TNVSQVLSSV DQISSSLSKL
KRGTKATAAD VLSDDGKIKL QLQLDLFKVK TVLDSLPLPD DCDAYSTLSR LTKEVGGLLQ
//
