ID A0A085NSE3_9BILA Unreviewed; 1417 AA.
AC A0A085NSE3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Fibronectin type III domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=M514_05382 {ECO:0000313|EMBL:KFD72389.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD72389.1};
RN [1] {ECO:0000313|EMBL:KFD72389.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD72389.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
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DR EMBL; KL367477; KFD72389.1; -; Genomic_DNA.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00406; IGv; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1417
FT /note="Fibronectin type III domain protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001796243"
FT TRANSMEM 1074..1098
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..121
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 132..216
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 232..317
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 322..406
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 424..517
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 523..627
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 632..729
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 734..828
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 837..938
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 940..1037
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1181..1200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1282..1296
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1417 AA; 154680 MW; 900DC6119B744789 CRC64;
MHDFPPLLCI VFLAVVEPLL GLNSAPNVRF VVEPADALVS KGQEVRFDCA IAGADDETVD
VQWRLNGITL DRRMRTYVLP NSSLVIPPTA NALLSPQLSD RTSADCYQCV VTVNNQWVYV
SRKAKLQYID AAHFKEEPSN RHVAEGSTVI IPCRLQGRPS ASPLKVTWLK DGAPLPDMPK
RITASAEGGF LEIRSVQFSD NGLYSCKVDV GSETLSSRQG RVAVTSKSDD DLKFEMKPKN
QRVNVGGSAF LLCSINGRLK PKVVWLKGSA EVKYTSRVRL VGESSLLIAN VQPDDRGTYT
CKASTSERTE SSSALLEVMT LPDFSSRPEN VVGLANQAIT FRCEAKGYPS PAITWYKNGE
VLKSSEYFMI NDTHLKISGL VKNDQGVYQC LAENDVGSVQ SSAVLLVEAS DSPAKLLIAA
GSREPTGLQA VHISSRYVML RWSSPTAWNQ TVTGYSVFYK SLDTQREHQL NCTPPENRGY
TVSGLLPKKT YYFRVVPISS VGYGSSSSTI TVATAEEKDN PSAVQHLNAY AVSSTSIQIE
WDPPETHARE PIKFYKIFYA AVGLGSQSEL GPSVGLDVEE TEIQSRNTAY VLHGAKEYTK
YRIRVEAFRD DGSSHSSAPV YVRTFSDKPT ATPTAFSVLA LASDKALVRW SPPPADGCNG
EIVTYRIRYR MKDRGSRSQN IVVESPKMET TINDLVAGAT YVFRVAAATI NGTGPFTPWK
EVVMTVYEGE ESHVPGGPTS LHLQATSNEI SLTWTPPRDD GNLIRGYLVG WGINVPDIET
QRVPGNSRTF VIRKLRPNKD YVVSLKAFNR LGNGFPIYET VRTEDKSSKD VSVSVETPIG
LRAVTLSSTA ISLSWTDRNQ GTLPPNIQND DCYYTVRYTS HYVSGGRYRY VNTSESSYVI
DGLKPDTQYE FSVKAALGRF ESEWSMTAFN KTFSSAPSSA PRDLTTIDSD SDPTSVLLNW
QPPKHPNGKI TKYLIYYTSE PKLTDSSWMI EGIRGDRMST TIDGLIPEKD YFFKIQAVND
RGYGPVSAVK PYRARRMKSV LGPVDSANRV PGVIHAEATS TGSPSADTSF SWNALSLIIA
VVSGIVVILV IALVVYLYRQ RKGRTRGYTA GVKKTLRDSK PPPDLWIHHE HHSVEMRGVE
GKNSGLDGSS FCDLMQMKSC RTPTPPMPDV PRYQSLAHVQ PANGSLSRKR HHLSSSSVDA
AALNSPRSCA VGHSQKAPQV VYTGPKASAR AQLLMSDCSA SEECVPTSPM PTPPVSSGGG
DSHSDASGPT GRSSNPLKSF ALLSVPPPPP PPISNISPNS TAGRMHLVRP TTAVGPSAFS
SPKSRATNSG SFGSKGKRSQ VHVQQQQQQQ QQQQPPRSSP SSQRMTGSVT GNNGYGGKDA
DGEVMRSYST EELTAQMQNL DNLMQDLNAI SANEFDL
//
