ID A0A085TUU4_9RHOB Unreviewed; 604 AA.
AC A0A085TUU4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Peptidoglycan synthetase FtsI {ECO:0000313|EMBL:KFE34491.1};
GN ORFNames=DW2_13100 {ECO:0000313|EMBL:KFE34491.1};
OS Thioclava atlantica.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Thioclava.
OX NCBI_TaxID=1317124 {ECO:0000313|EMBL:KFE34491.1, ECO:0000313|Proteomes:UP000028607};
RN [1] {ECO:0000313|Proteomes:UP000028607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13D2W-2 {ECO:0000313|Proteomes:UP000028607};
RA Lai Q., Li G., Shao Z.;
RT "Thioclava sp. 13D2W-2 Genome Sequencing.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KFE34491.1, ECO:0000313|Proteomes:UP000028607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13D2W-2 {ECO:0000313|EMBL:KFE34491.1,
RC ECO:0000313|Proteomes:UP000028607};
RX PubMed=25361528; DOI=10.1007/s10482-014-0320-3;
RA Liu Y., Lai Q., Du J., Xu H., Jiang L., Shao Z.;
RT "Thioclava indica sp. nov., isolated from surface seawater of the Indian
RT Ocean.";
RL Antonie Van Leeuwenhoek 107:297-304(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFE34491.1}.
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DR EMBL; AQRC01000010; KFE34491.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085TUU4; -.
DR STRING; 1317124.DW2_13100; -.
DR PATRIC; fig|1317124.6.peg.2652; -.
DR eggNOG; COG0768; Bacteria.
DR Proteomes; UP000028607; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 86..222
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 260..557
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 65606 MW; 653ECE6B760A1D63 CRC64;
MRTPLRPLPR ILDARAKGEN PDAIERENRR LRGEATRDKS RQRAEGRLLV MSVLFLAAFL
TVGLRMGSFA AARPEEPQTD ASSQQIYSQR ADIVDRKGRV LATNLLTHAL YAQPPMMIDP
TGTADKLVKI FPDLDRDRLI KDFTGARKFV WIKKRISPEQ LQAVHDIGDP GLLFGPREMR
LYPNGHLASH ILGGARYGTE GVNSAEILGV AGIEREYDKW LRDPANGGKS LKLSLDLTVQ
SALEDVLSGG MKLMNAKGAT AVLMKARTGE IVAMASLPDF DPNDRPAPLL KGDPSDSPLF
NRAVQGVYEL GSTFKIFAVS QAMQMGLVTP ETMIDTKGPL RWGKFRIHDF HDYGKQLSVT
DVIVHSSNIG TARIVQKIGP EKQREFLGKL GLLEPAPVEL IEAPTGRPIL PQNWSELSAM
TIGYGHGLSD SPLQLAAAYA TIANDGKRVL PTLIAKGGPR EPVKQEFGAA EGAQVVSPEV
AHKALAMMRA VVTRGTASYG DVPGYQVAGK TGTADKPDPQ GGYYNDKVIS TFAGVFPVTD
PQYVLVLTLD EPTDTSGNEP RRTAGWTAVP VAAETIRRVA PLLGLRPEPT TPDTLDGIRL
VKKD
//
