ID   A0A085VQY4_PSESX        Unreviewed;       633 AA.
AC   A0A085VQY4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Acetylneuraminic acid synthetase {ECO:0000313|EMBL:KFE57847.1};
GN   ORFNames=IV01_01940 {ECO:0000313|EMBL:KFE57847.1};
OS   Pseudomonas syringae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=317 {ECO:0000313|EMBL:KFE57847.1, ECO:0000313|Proteomes:UP000028631};
RN   [1] {ECO:0000313|EMBL:KFE57847.1, ECO:0000313|Proteomes:UP000028631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GAW0119 {ECO:0000313|EMBL:KFE57847.1,
RC   ECO:0000313|Proteomes:UP000028631};
RA   Baltrus D.A., Berge O., Morris C.;
RT   "Draft Genome Sequences of Environmental Pseudomonas syringae strains.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFE57847.1}.
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DR   EMBL; JPQU01000015; KFE57847.1; -; Genomic_DNA.
DR   RefSeq; WP_032625489.1; NZ_JPQU01000015.1.
DR   AlphaFoldDB; A0A085VQY4; -.
DR   PATRIC; fig|317.175.peg.414; -.
DR   OrthoDB; 9781701at2; -.
DR   Proteomes; UP000028631; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   Gene3D; 3.20.20.150; Divalent-metal-dependent TIM barrel enzymes; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   PANTHER; PTHR42966:SF3; BLR5971 PROTEIN; 1.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   SUPFAM; SSF51658; Xylose isomerase-like; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
FT   DOMAIN          291..349
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   633 AA;  70922 MW;  2792856996D5C083 CRC64;
     MNKQVFTIDG AVIGGDHVYV IAEVGNNHNG SVELAKQLVD ASIESGADCV KFQLRNREAL
     YRTKADGSRA EDLGVEYIQD LLDKVELTVE EHRQIRDYCK QQGISYICTP WDEPSVDVLA
     GFDVPAFKIA SADLCNPYLI AKAASLGKPL ILSTGMSLEH EIVRTIEQLQ DLGVPFALLH
     CNSTYPAPES DIQLGYIARL KELHGLIGYS GHERGTAITI AAVALGAKLV ERHITLDRGM
     EGPDHLASLE PLEFRQLVDG IRQVQKALPW AGPGRHASQG ELLNRENLGK SVIAARAIDK
     GEVFVQSMLR VASPGQGLPP YRLSDLLGKP AGRKIEQGDF LFDSDLSEQQ EVRRDYDMPI
     LWGVPVRYHD FLQYNEWIKP DLFEFHLSYR DLSVAPQPFL RTVECSRLVV HAPELFENSE
     LLDLVSDDLE YRQRSIDNLQ RVVDATLQMA EFFPKADSLL IVANIGGFSA DEPLPFSHRA
     ELYERFRESC AQIDFGRTEL IPQNMAPFPW HFGGQRHQNI FMMPDELAEQ AKRLNMRLCL
     DLSHLQMTCF HFELDFQAAL KLLLPYSAHL HVADAKGANG EGVIMGTGDV DWPATWAQLK
     GYPNVSFIPE VWQGHKDHGA GFWSALEFLN ELN
//