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Database: UniProt
Entry: A0A086PAS3_SPHHM
LinkDB: A0A086PAS3_SPHHM
Original site: A0A086PAS3_SPHHM 
ID   A0A086PAS3_SPHHM        Unreviewed;       470 AA.
AC   A0A086PAS3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KFG90491.1};
GN   ORFNames=BV98_001695 {ECO:0000313|EMBL:KFG90491.1};
OS   Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC
OS   16415 / MH) (Sphingomonas herbicidovorans).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1219045 {ECO:0000313|EMBL:KFG90491.1, ECO:0000313|Proteomes:UP000024284};
RN   [1] {ECO:0000313|EMBL:KFG90491.1, ECO:0000313|Proteomes:UP000024284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 16415 {ECO:0000313|EMBL:KFG90491.1,
RC   ECO:0000313|Proteomes:UP000024284};
RA   Gan H.M., Gan H.Y., Savka M.A.;
RT   "Draft genome sequences of Sphingobium herbicidovorans.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFG90491.1}.
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DR   EMBL; JFZA02000012; KFG90491.1; -; Genomic_DNA.
DR   RefSeq; WP_037464638.1; NZ_JFZA02000012.1.
DR   EnsemblBacteria; KFG90491; KFG90491; BV98_001695.
DR   PATRIC; fig|1219045.3.peg.1731; -.
DR   Proteomes; UP000024284; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000024284};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895}.
FT   DOMAIN      166    300       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      378    447       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     174    181       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  51807 MW;  C98D8FE3D3BB5091 CRC64;
     MKGLIAVSGS SSVQASHDHA RLDTAWDAIR TGLRRDIGPR MFDQWLKAGQ LGDYCAESQT
     LDLLFASDFT ANFVSAHFGD RLRMAWRCAG VGVREVRLRR APNAVGPRLL EVAPAQEAVS
     TDPILPEGVS ACNFQPRHSF ADFVTGDSNH LAFSAAEAMA GEAQPRYSPL FIHGSTGQGK
     THLLHAIAQH FSAHSPNAPV LYMSAERFMM EFVNAMRANE TMMFKARLRA ARLLLIDDIQ
     FIAGKGSTQE EFLHTINDLI DSGARIVVTA DRAPQQLDSI DARILSRLAG GLVADIRPAD
     LDLRLAILET KRAIAGDPPV PDAVIDFLAR SIRSNIRELE GAFNKLIAYG QLTGRSVDLE
     FAQTMLADAV RANARRITVD EIQKVCAAHY KIDASEMRSK RRARAVARPR QVAMYLAKKM
     TPRSLPEIGR IFGGRDHSTV IHAVRTIEEL RQTNADIDAD IRALLRQLEN
//
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