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Database: UniProt
Entry: A0A086ZSN6_9BIFI
LinkDB: A0A086ZSN6_9BIFI
Original site: A0A086ZSN6_9BIFI 
ID   A0A086ZSN6_9BIFI        Unreviewed;       541 AA.
AC   A0A086ZSN6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BBIA_0963 {ECO:0000313|EMBL:KFI49536.1};
OS   Bifidobacterium biavatii DSM 23969.
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=1437608 {ECO:0000313|EMBL:KFI49536.1, ECO:0000313|Proteomes:UP000029108};
RN   [1] {ECO:0000313|EMBL:KFI49536.1, ECO:0000313|Proteomes:UP000029108}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23969 {ECO:0000313|EMBL:KFI49536.1,
RC   ECO:0000313|Proteomes:UP000029108};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFI49536.1}.
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DR   EMBL; JGYN01000023; KFI49536.1; -; Genomic_DNA.
DR   RefSeq; WP_033494985.1; NZ_JGYN01000023.1.
DR   EnsemblBacteria; KFI49536; KFI49536; BBIA_0963.
DR   Proteomes; UP000029108; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029108};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029108}.
FT   DOMAIN      229    368       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      444    513       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     237    244       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   541 AA;  59646 MW;  9A973FE42583E509 CRC64;
     MAHTPQDPAA QAARIWADAL ALLKHNSKLT ARDKGWLEGV VPEAVFGTTI VLSVENLATQ
     QALQKELNQP LLHALSIASG TSMFPAFKVE PRQEQPAEPE PEPVSAQQAK QNTFAKEFDA
     RSAPTVSDLS QDAYRADESA PRINRPLPTV ATPSVRPAPA GTMPASMPSQ QSMPSAIPEG
     TFTASRTQVA RDPQTHLNKN ATFDTFVPGD SNRFARTVAL AVAEGSGRDF NPLCIYGGSG
     LGKTHLLNAI GNYALVKDPT LKVRYVTSEE FTNEFIEALS DTNKSQGQIA EFNRRYREVD
     VLLIDDIQFL GGKEATLEQF FHTFNALYQA NKRIVIASDV APKNLKGFEA RLISRFESGL
     PVDVKPPDLE TRIAILRMMA SMNHTNIPND VLDLIAERFT ENIRELEGAL TRVTAVASLS
     NQPVTPALAE QTLQDFFTTD VEIKPTDIIG QVAKYFHLTF DDLVGRGRTK NVSIARQIAM
     YLSRENTGMS LVDIGEVFGG RDHTTVMHAV EQINAKMQQK QEIYNYVMEL TLRLKQHSND
     D
//
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