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Database: UniProt
Entry: A0A087A068_9BIFI
LinkDB: A0A087A068_9BIFI
Original site: A0A087A068_9BIFI 
ID   A0A087A068_9BIFI        Unreviewed;       527 AA.
AC   A0A087A068;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 27.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BCAL_2091 {ECO:0000313|EMBL:KFI52168.1};
OS   Bifidobacterium callitrichos DSM 23973.
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=1437609 {ECO:0000313|EMBL:KFI52168.1, ECO:0000313|Proteomes:UP000029072};
RN   [1] {ECO:0000313|EMBL:KFI52168.1, ECO:0000313|Proteomes:UP000029072}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23973 {ECO:0000313|EMBL:KFI52168.1,
RC   ECO:0000313|Proteomes:UP000029072};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFI52168.1}.
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DR   EMBL; JGYS01000018; KFI52168.1; -; Genomic_DNA.
DR   RefSeq; WP_043166249.1; NZ_JGYS01000018.1.
DR   EnsemblBacteria; KFI52168; KFI52168; BCAL_2091.
DR   Proteomes; UP000029072; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029072};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029072}.
FT   DOMAIN      213    352       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      428    497       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     221    228       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   527 AA;  58417 MW;  8CC7947CE00DD28F CRC64;
     MAAQSNDPVA HANRIWSDTL SLLKHNKTLS ARDRGWFEGV YPEAIFGTTI VLCVENTGTR
     QALENELNQP LLDALHMVTG EEMTPAFKIV KRKSAKSHGS TVKIAKTARS GRSATATIPQ
     RPQTVSELSH EPFGAGGPVP HVPADMPANM PGPIATQNTA PTRPEYPISS NRVAQDPQTH
     LNKNATFDTF VPGDSNRFAR TVALAVAEGS GRDFNPLCIY GGSGLGKTHL LNAIGNYALV
     KDPTLKVRYV NSEEFTNEFI EALQNPNQSQ GQIAEFNRRY REVDVLLIDD IQFLGGKEAT
     LEQFFHTFNA LHQANKRIVI ASDVAPKNLK GFEARLISRF DSGLTVDVKP PDLETRIAIL
     RMMASTNHSN IPNDVLDLIA ERFTENIREL EGALTRVTAV AALSNQPVTR AMAEQTLQDF
     FTTDVEVKPT DIISQVARYF HLTFEDITGK SRMKNIAIAR QVAMYLTREM TSLSLVDIGK
     VFGGKDHTTV MHACDRISNE MQERQEVYNY VMQLTVRLKQ GNSDLRQ
//
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