ID A0A087AQX1_9BIFI Unreviewed; 787 AA.
AC A0A087AQX1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=BIGA_0603 {ECO:0000313|EMBL:KFI61171.1};
OS Bifidobacterium pullorum subsp. gallinarum.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=78344 {ECO:0000313|EMBL:KFI61171.1, ECO:0000313|Proteomes:UP000029046};
RN [1] {ECO:0000313|EMBL:KFI61171.1, ECO:0000313|Proteomes:UP000029046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 11586 {ECO:0000313|EMBL:KFI61171.1,
RC ECO:0000313|Proteomes:UP000029046};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFI61171.1}.
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DR EMBL; JGYX01000002; KFI61171.1; -; Genomic_DNA.
DR RefSeq; WP_033506035.1; NZ_JGYX01000002.1.
DR AlphaFoldDB; A0A087AQX1; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG2815; Bacteria.
DR OrthoDB; 9762169at2; -.
DR Proteomes; UP000029046; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 2.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 4.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KFI61171.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029046};
KW Transferase {ECO:0000313|EMBL:KFI61171.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 453..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..285
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 570..644
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 645..711
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 301..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 787 AA; 83348 MW; 629C8EC30BBA2682 CRC64;
MTEAANVPDG LVIEGRYRIV RRIAEGGMAT VYQAMDERLD RTVAIKIMHT QLAQGPHREQ
FVERFRREAK SAAAIANPHI VQVYDTGEYN GLDYLVMEYV HGVNLRHEMN TQRTFTVRET
LRILSETLDG LSAAHRIGVV HRDIKPENIL LNDRGRVQIT DFGLAKAASQ ATLSTTNMLL
GTAAYLAPEM IEHNQATPQG DLYSVGITAW EMLAGFVPFQ SDNPVTLVFK HVHEDVPSVA
DPCPGIDPSI AAFIAHLTAR AVDARPADAV EAMRELRELT AHLPMTAWQY RKPTVAPAPA
ATTALPPLPP VAADPTTPTS ADASAHVDTP VTADAPSAVT AAIQAQQTTA MSQPPAAPAD
GTATAAFAPD ATQAIDRSPE SATSIIDVNA TQNLPAVGAP AQAIAQPDAV HATSAGIAST
QVIGAVDAPE ATPDAAPAAD EQPKAHTSRR RTAVIVTVVV LLIAAIGGGG FAWWYFRGPG
SYWTLPQPND ITCTEGRDCP ITDADWDDYR SALTVADIPY TTAEDFSDTV DEGNIIAVHL
TADASAKPLN VGDHVSRRDG SQITVTVSKG VRQATIPEDI LDPDSANAKD PLQALQDAGF
DNVVHDEDND QYSETLAAGV ALTISPDPGT TLDHNAEVTV TLSKGPAPVQ MPTVEGLTRD
QMNEALTELK LTANVTEEFS DSVPSGQVIS ASVEPGAELH WGDTVDVVVS KGPETAAVPS
GLVGKQESEV TKTLQGLGFK VETNRILGGL FGTVRDVQYN GESISDGANV RLRDADGNAS
VITLTVV
//
