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Database: UniProt
Entry: A0A087B7Y0_9BIFI
LinkDB: A0A087B7Y0_9BIFI
Original site: A0A087B7Y0_9BIFI 
ID   A0A087B7Y0_9BIFI        Unreviewed;       612 AA.
AC   A0A087B7Y0;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BMAGN_1342 {ECO:0000313|EMBL:KFI67130.1};
OS   Bifidobacterium magnum.
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=1692 {ECO:0000313|EMBL:KFI67130.1, ECO:0000313|Proteomes:UP000029052};
RN   [1] {ECO:0000313|EMBL:KFI67130.1, ECO:0000313|Proteomes:UP000029052}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 11591 {ECO:0000313|EMBL:KFI67130.1,
RC   ECO:0000313|Proteomes:UP000029052};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFI67130.1}.
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DR   EMBL; JGZB01000011; KFI67130.1; -; Genomic_DNA.
DR   RefSeq; WP_022860238.1; NZ_JGZB01000011.1.
DR   EnsemblBacteria; KFI67130; KFI67130; BMAGN_1342.
DR   Proteomes; UP000029052; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029052};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029052}.
FT   DOMAIN      298    443       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      517    585       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     306    313       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   612 AA;  68155 MW;  2EC2F3F969427650 CRC64;
     MADDMLDPAI AANHIWSDAL AFLRSDRRAN LTERDKGWLE GIMPETAFGS TIVLCAENTT
     TMEMLQSKLS KPLLQALWIA NGKPITPAFK IVSDEEFSRL KAFREETLES KPHTPSTPPD
     TLSSVPNETP MQSMASMPSM PAMQPVQPMM PMMPMQDFQQ VQNVQNVQNG AAFAPATAPQ
     VQNQQPEQLT FASALEEEEP EESPLSSVYK DSAYSSKSYV TRHLPSPMQG ELPIAAAGPM
     PEQARPRPMG ANNSQIPNMD PVTHLNKSAT FDTFIRGESN KFAYTVSLAV AEGTGRAEFN
     PLFIYGHSGL GKTHLLNAIG NYAIECAQEA GEELSVRYVT SEEFTNEFIE SLQSGTKNSS
     LTSEFNKRYR SVDILLIDDI QFLSGKEQTL DQFFYTFNSL QQAGKNIVIT SDVVPKNLKG
     FEDRLISRFE QGLTVDVQPP DLETRIAILQ SISAGNYMKV PDEVLSIIAE RFTSNIRELE
     GALRRVTARA NLSHMPVTPE LAELALQDLR TSEVEVTPAQ IINQVATYFH LTFDDIMGKA
     RQRNVVLARQ IAMYLTNELT SKSLKEIGRE FNKDHSTVIH ARDVISTRMA DKQEIFKYVN
     ELTARIKQEA DA
//
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