ID A0A087DI79_9BIFI Unreviewed; 373 AA.
AC A0A087DI79;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:KFI95229.1};
DE EC=1.1.1.205 {ECO:0000313|EMBL:KFI95229.1};
GN ORFNames=BSCA_1047 {ECO:0000313|EMBL:KFI95229.1};
OS Bifidobacterium scardovii.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=158787 {ECO:0000313|EMBL:KFI95229.1, ECO:0000313|Proteomes:UP000029033};
RN [1] {ECO:0000313|EMBL:KFI95229.1, ECO:0000313|Proteomes:UP000029033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21589 {ECO:0000313|EMBL:KFI95229.1,
RC ECO:0000313|Proteomes:UP000029033};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFI95229.1}.
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DR EMBL; JGZO01000004; KFI95229.1; -; Genomic_DNA.
DR RefSeq; WP_033519369.1; NZ_JULC01000147.1.
DR AlphaFoldDB; A0A087DI79; -.
DR STRING; 158787.BSCA_1047; -.
DR GeneID; 85166022; -.
DR eggNOG; COG0516; Bacteria.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000029033; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KFI95229.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029033}.
FT DOMAIN 17..298
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 373 AA; 39491 MW; 1938CBCC7F532B8C CRC64;
MSQEIEIGLG KKGRLAYSLD DVAIVPSRRT RDPEAVSTAW QVDAYEFDVP VIGAPMDSVT
SPATAIAMGK LGALGVLDLE GLWTRYENPE PLFEEIASLP AEDATRRIQE IYAEPIKAEL
ITARLHEIRN AGVTVAGSLS PQHVQEFYST VVGAGVDLFV IRGTVVSAEH VSDGHEPLNL
KKFIYDLDVP VIVGGAANYT AALHLMRTGA AGVLVGFGGG AVSATRTTIG VHAPMATAIA
DVAEARRDYM DESGGRYVQV IADGGMGDSG SFVKALAMGA DAVMLGAPLA RATEAPGRGK
HWGAEARHQT LPRGYRTDVG TVGSLEQILF GPSHQADGQV NYIGALRRAM ASTGYVDVKN
FQRCSVVVTP YGR
//
