ID A0A087FWS0_ARAAL Unreviewed; 1564 AA.
AC A0A087FWS0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=AALP_AAs48547U000400 {ECO:0000313|EMBL:KFK22072.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK22072.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
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DR EMBL; KL992886; KFK22072.1; -; Genomic_DNA.
DR EnsemblPlants; KFK22072; KFK22072; AALP_AAs48547U000400.
DR Gramene; KFK22072; KFK22072; AALP_AAs48547U000400.
DR eggNOG; KOG0017; Eukaryota.
DR OrthoDB; 463649at2759; -.
DR Proteomes; UP000029120; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120}.
FT DOMAIN 1517..1564
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 48..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1318..1337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1351..1392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..135
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1377..1391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1564 AA; 177451 MW; 3D68945940A4EEFA CRC64;
MKCQRGHRVS RRRCRDQDCL APMSRSSDTD DRQXXXCHCP VTPMCLASSV PRQLTSTPKP
FHRLQVLQRP SEHQRGFQKV QHVKAQLQSP RRLDRHRRKR LPHRAEEASQ DDRGKLEGTE
SSFAKKTRKT QHGETQSARR PSAPRTTRGN PEDLPPPPPS RETDKSPERV VDVSDEEEPA
TAKRTRAEGA EGNRREPRAR DTQSASSSSK TEIVGDTAEY SNYSSKERYK KEQERRAFKR
SYAAVKAQMD RVTSDLKHTQ SQMHQGTGKA PAIAQVLEKA RNTPFDERIA KTKISDPGRI
KLPIYEGTTD PSDHLMEFEV ALGRANFKEA EKDIVYCKLF VESLKGPTLQ WFYKLEKNSV
HTFLQLSELF VQHYNIFMER KIYDSELWNN KQGETESLRS CMTRFKNTLS KVEGISNKSA
LEALRGALRC PSPFWQEMSL NTPITIQDAL HRAADFARTE EEVQARKGGK SKQASGHSTA
RCRELGRQLI AKLTEGTLKN NNNLSDFKPE EKAPANVEEQ ADTPRCQRRD DGMENEHQYE
VINMIMGGSQ YCADNETAIE AYQRRADVCA NISTPAKPRL SSDLIIFDEK DTEGLDQPHN
DPLVINLTIY DFNVARVLID TGSSVDVIFK KTLERMKIDL STIKGRPKPI TCFSGETTMT
MGTIRLPVQA GNIKKMVDFT VSDHPAIYNM IMGTTWLNLM RAVPSTYHLC LKFPTPIEGR
VDEERPTCEP VVSICTDEQH PERCVEIGAT LDEDIKKKLV VFLQKNINTF TWAAEDMPGI
DINVASHELN VDPTFKPIKQ KRRKLGPDRA KAVNDEVERL LRVGSITEVK YPDRLANPVV
VKKKNGKWRV YVDFTDMNKA CPKDSFPLPH IDRLVEATTG NKLLTFMDAF SDYNQILMHP
KDREKTAFIT DRGIYCYKVM PFGLKNAGAT YQRLVNKMFR DQLGKTMEVY IDDMPVKFLE
EEDHISHLEA CFEQLNLHNM KLNPTKCRFA LTSGEFLGYL VTRRGIEANP KQIDALIQMA
SPRNKREVQR LTGRVAALNR FISRSTDKCL PFYDTLRGNK QFEWSNKCED AFRQFKEYLA
TPPILAKPVT GEPLFLYIAV SETAVSAVLI REERGEQKPI FYSGRLAKWA IELSEYDIEY
KGRTCNKSQV LADFLIELPE DQSAKEVRPG IWELHVDGSS SKNGSGVGIR LASPTGEILE
QSFRLGFRAS NNEAEYEAII AGMRLAQGLN IEHVHAFCDW QLVSNQFSGE YATKDGRMEA
YQKIVKDLAL TFKEFTLTRI PREENVDADA LANLASASAP PKDPTLKPVI PVEDVEMTEA
EANTEPAPST TPTSDAYAIG PEVIGADVTE AEDPEDLRQP EELPTQNLPL EPIDKDMTVP
MDTDEEPEYG CDKPWMNQIR AYIISGKLPN SKWAARKVQK QAARYVLLDD NIYRRGFSGP
VLTCVEGQDA RQVMEEIHSG SCGNHSRGKA LAIKIKRHGH FWPTIVNDWV KFSAKCERCQ
RHAPKIHQPT EKLSSVTSLY PFMRWAMDIV GPLHASKQKR FLLVLTDYFS KWVEAEAYAS
IKDA
//
