ID A0A087GCC1_ARAAL Unreviewed; 511 AA.
AC A0A087GCC1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=MBD domain-containing protein {ECO:0000259|PROSITE:PS50982};
GN OrderedLocusNames=AALP_Aa8g394200 {ECO:0000313|EMBL:KFK27523.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK27523.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM002876; KFK27523.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GCC1; -.
DR EnsemblPlants; KFK27523; KFK27523; AALP_AA8G394200.
DR Gramene; KFK27523; KFK27523; AALP_AA8G394200.
DR eggNOG; KOG4161; Eukaryota.
DR OrthoDB; 509339at2759; -.
DR Proteomes; UP000029120; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd01396; MeCP2_MBD; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR006462; MS5.
DR PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR PANTHER; PTHR12396:SF38; METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 7; 1.
DR Pfam; PF01429; MBD; 2.
DR Pfam; PF04776; protein_MS5; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 3.
DR PROSITE; PS50982; MBD; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 224..299
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 316..382
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 383..453
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 85..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 58939 MW; 65167E9561D74AFF CRC64;
MRSRYWRGVW KSDGFDLEGL EEITPPLNGL ITCRFESQSD YRTQIVLYAK FGIHEYNARH
GKNLQFSCME KFNYLPEFTQ FRPQEKPLEP SSNQEEEEEP EPYNYGDKIL PEWPSENALR
DKSRFYLLKK SDLKKYGWIR LYLELAFFKA NIKLKKLDLT KLVIGRVAVE SRQENVEPPT
ERLNAVNSVI YIKYNMQTRS SSSASGELVP LGVQFPAIYH QLQIVDPISF RGKLLPGWTV
VNHPRSLSPS NNGSVDTYFI EPGTGRQFPS LESVQRHLTR AGAFFREKTR VYEGSRTKQV
SSVYEGSRTK QNHRSLEYAS KSFRLPAKGW TIEEYPRKNS YHIDKYYVER STGKRFRSLV
SVERYLNESG NHADHQQPML LQYHRVNSKD FSLPDGWIVE EKPRINSTHV DKTYIEPGTG
NKFRSMAAVK RYLEATGNST LDLVSMEHSE RLSLTGFQAE VIDPNPPKKV KWVLTGSDGN
TFTANMSGSD VSSSVKQKWS EAFVSLIQDR S
//
