ID A0A087GUT6_ARAAL Unreviewed; 515 AA.
AC A0A087GUT6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Methyltransferase small domain-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=AALP_Aa5g039700 {ECO:0000313|EMBL:KFK33638.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK33638.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RNA M5U methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01024}.
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DR EMBL; CM002873; KFK33638.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GUT6; -.
DR EnsemblPlants; KFK33638; KFK33638; AALP_AA5G039700.
DR Gramene; KFK33638; KFK33638; AALP_AA5G039700.
DR eggNOG; ENOG502QTKF; Eukaryota.
DR OMA; WRLEKAH; -.
DR OrthoDB; 1215241at2759; -.
DR Proteomes; UP000029120; Chromosome 5.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.40.50.1070; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR010280; U5_MeTrfase_fam.
DR PANTHER; PTHR47548; BNAA06G32370D PROTEIN; 1.
DR PANTHER; PTHR47548:SF1; S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF03602; Cons_hypoth95; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51687; SAM_MT_RNA_M5U; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01024}; Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01024};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01024}.
FT ACT_SITE 454
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 282
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 309
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 332
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
FT BINDING 380
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01024"
SQ SEQUENCE 515 AA; 57492 MW; 3E12B545F0C609C3 CRC64;
MHSSSLFSFG ARYPIISCRV SPPPPSPSLV ASLPLPSISS DSDVDSQAKS LACSLQCPHF
QSCSGCTQEF NLHRPNVVDE ASGFFKRYGV EDFTFDSCRL WGWRCRAKLA VRGSSDNALI
GLYQEGTHTV VDIPDCKSHH PNINAAIELL REGIKVFDVE PFDEDQNTGD LRYVQMAVTT
HSTSLRAPER YKNGKVQVSL VWNSRNEKSH NADKLQALSS YLWRKGGPNS KFHLIHSVWA
NFQTSTNNII FGNRWRHLLG ERDFWEHVGG IDISLDPSSF GQANTRAFDS LLWKLHKYVP
GGSSVADLYA GAGVIGLSLA TSRKCSSVKC IEVNKEARLS FEKSIQRLPN SLNCSISWHH
ADASVNPLSW IIGTDVVVVD PPRRGLDASL RQILESVPSI EKRMRSSSPS SSSTAKEEKR
PWILRAKELS IQAGNKLIPE ESKTLPQRLI YISCGWESFK EDCKSLLSSR AWELENAHGF
NFFPGTDSIE VLAIFKRRVV TKKKKKSGIK KVRSK
//
