ID A0A087H1U2_ARAAL Unreviewed; 594 AA.
AC A0A087H1U2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=3,4-dihydroxy-2-butanone kinase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=AALP_Aa4g076600 {ECO:0000313|EMBL:KFK36094.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK36094.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002872; KFK36094.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087H1U2; -.
DR EnsemblPlants; KFK36094; KFK36094; AALP_AA4G076600.
DR Gramene; KFK36094; KFK36094; AALP_AA4G076600.
DR eggNOG; KOG2426; Eukaryota.
DR OMA; CGLCLKT; -.
DR OrthoDB; 6043at2759; -.
DR Proteomes; UP000029120; Chromosome 4.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004371; F:glycerone kinase activity; IEA:InterPro.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.340; -; 1.
DR InterPro; IPR012734; DhaK_ATP.
DR InterPro; IPR004006; DhaK_dom.
DR InterPro; IPR004007; DhaL_dom.
DR InterPro; IPR036117; DhaL_dom_sf.
DR NCBIfam; TIGR02361; dak_ATP; 1.
DR PANTHER; PTHR28629:SF13; DIHYDROXYACETONE KINASE; 1.
DR PANTHER; PTHR28629; TRIOKINASE/FMN CYCLASE; 1.
DR Pfam; PF02733; Dak1; 1.
DR Pfam; PF02734; Dak2; 1.
DR SMART; SM01120; Dak2; 1.
DR SUPFAM; SSF82549; DAK1/DegV-like; 1.
DR SUPFAM; SSF101473; DhaL-like; 1.
DR PROSITE; PS51481; DHAK; 1.
DR PROSITE; PS51480; DHAL; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 11..341
FT /note="DhaK"
FT /evidence="ECO:0000259|PROSITE:PS51481"
FT DOMAIN 381..585
FT /note="DhaL"
FT /evidence="ECO:0000259|PROSITE:PS51480"
FT ACT_SITE 226
FT /note="Tele-hemiaminal-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-1"
FT BINDING 62..65
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-2"
FT BINDING 118
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-2"
SQ SEQUENCE 594 AA; 61503 MW; 4DA9C847E4DDCEF9 CRC64;
MALPPKKFIN NPNDVVIEFI EGLVETYPGL QYLDGLPEVK VILRSDVSAA NYDKVAVISG
GGSGHEPAQA GFVGEGMLTA AICGDVFASP PVDSILAAIR AVTGPKGCLL VVTNYTGDRL
NFGLAAEEAK TEGFKVETVI VGDDCALPPP RGIAGRRGLA GTILVHKVAG AAAAAGLSLA
EVAVEAKHAS EVVGTMGVAL SVCALPGQAT SDRLGPEKME LGLGVHGEPG AAVVDIQPVD
VVVSHVLQQI LSPETNYVPI TRGNSVVLMV NGLGGTPPME LMIAAGKAVP KLQLEFGLAV
DRVYTGSFMS SLDMAGFSIS IMKADQSILQ RLDAPTKAPS WPVGTEGSRP PAKIPVPLAP
FQSTKNKESL SRPQELSPQG RLLEAAIETA ATVVINLKDS LNEWDGKVGD GDCGSTMCRG
ATAILEDMRN YYPLNDAAET VSEIGSSIRR VMGGTSGIIY SLLCKAAYAE LKANGQTEIS
PKRWSEALKS SVLAIGKYGG ASAGYRTMLD ALIPASKVLE EKLNAGEDSI SAFVQSAEAA
TTGAESTIQM QAQAGRSSYV SAENLASIPD PGAMAAAAWY SAAARAVKEL SQGL
//
