ID A0A087HKN1_ARAAL Unreviewed; 1016 AA.
AC A0A087HKN1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN OrderedLocusNames=AALP_Aa1g026300 {ECO:0000313|EMBL:KFK42683.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK42683.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447}.
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DR EMBL; CM002869; KFK42683.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087HKN1; -.
DR EnsemblPlants; KFK42683; KFK42683; AALP_AA1G026300.
DR Gramene; KFK42683; KFK42683; AALP_AA1G026300.
DR eggNOG; KOG1339; Eukaryota.
DR eggNOG; KOG2166; Eukaryota.
DR OMA; VTHYLYS; -.
DR OrthoDB; 1213461at2759; -.
DR Proteomes; UP000029120; Chromosome 1.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR032799; TAXi_C.
DR InterPro; IPR032861; TAXi_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF138; CULLIN-1-RELATED; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR Pfam; PF14541; TAXi_C; 1.
DR Pfam; PF14543; TAXi_N; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1016
FT /note="Cullin family profile domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001823436"
FT DOMAIN 709..863
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 1016 AA; 115408 MW; 1E9EB63AAE828AC9 CRC64;
MTSSPIIFSF LLLFIFSFSS STSFAESPFR PRALILPVSK DKSTLQYTTV INQRTPLVSA
SVVFDLGGRN LWVECDKDYV STTYNSPRCN SAVCSRAGPR GCGQCFSPLR PGCNNNTCNS
FPDNTVTGTI TSGEIALDVV SIQSINGSKP GRVVKIPNFI FVCGSTFLLN RLASGTVGMA
GIGRHNIGLP SQFATAFNFN RKKFAVCLTS GRGVAFFGDV TYNFLPGIEI SPLTTTPLLI
NPVSTASAYT QGEKSAEYFI GVRDIKISDE SVPFNKSLLK INGASGYGGT KLSTVDAYTV
LETSIYNAFT SAFIRAATAR NISQVSSVKP FGACFSTANV GSTRIGYAVP DIQLVLHSKD
VVWRIFGANS MKPPHDYAHQ LYYRYCQLIE DYAKQTVLPS LKDKYDEYML KELVKRWSNH
KVMVKWLTFF FNYLDRFLVS RRALPTLNEV GLACLPYQVY RDPEMRSKAK DVVLTLIHKE
REGEQIDRAL LKNVLDIFVE NGVGKSEKYE EGFEIFILED TASYYSRKAS SWIQDDSFPE
YMLKTEECLK KERERVTHYL YSSTEPKLVK IVLKELSVVV AKQLQENEHL GFQALLRDDK
MDDLSRMYRI YHPIPQWLKL VADLFNKHVT AEGNILIKQV EDADTTQAAN TGGVQEQEVR
LQVLMRIVNE LRNKYMVYVT ECFQNNYLFH KALQEAFEIF CSKKVAGISI AELLATLCDN
LLKKGGNEKL SDEAIEARLE NLVEFLVYIS DKDLFAELYS KKLARRLLFD RSGNDEHERS
VLRKLKEQFG GQFISKMEGM VTDMTLAKEN QKSFQEYITS DVTENAGTDL TVTVLTSGFW
PSYKTCDLKL PSEMAAMLLL FNNTERLSYT DILEQLNLSH EDLVMLLHSL SCAKYKILKK
EPNSSSISQT DVFEFNSKFT NRMQRIKIPL PKLDERKKVV EDVDRDRRYA IDASLVRIMK
SRKVLDHQQL VSECVEHNSR MFKPDIMMIK KRIEELINRD YLERDNENRS ILKYVA
//
