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Database: UniProt
Entry: A0A087QM45_APTFO
LinkDB: A0A087QM45_APTFO
Original site: A0A087QM45_APTFO 
ID   A0A087QM45_APTFO        Unreviewed;       493 AA.
AC   A0A087QM45;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 {ECO:0000313|EMBL:KFM02299.1};
DE   Flags: Fragment;
GN   ORFNames=AS27_03074 {ECO:0000313|EMBL:KFM02299.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM02299.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM02299.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM02299.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL225740; KFM02299.1; -; Genomic_DNA.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   Gene3D; 3.90.190.10; -; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTPase_domain.
DR   InterPro; IPR014020; Tensin_C2-dom.
DR   InterPro; IPR029023; Tensin_phosphatase.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   Pfam; PF00782; DSPc; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF10409; PTEN_C2; 1.
DR   SMART; SM01326; PTEN_C2; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF49562; SSF49562; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS51182; C2_TENSIN; 1.
DR   PROSITE; PS51181; PPASE_TENSIN; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053286};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     41     65       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    108    127       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       99    352       Tyrosine-protein phosphatase.
FT                                {ECO:0000259|PROSITE:PS50055}.
FT   DOMAIN      177    353       Phosphatase tensin-type.
FT                                {ECO:0000259|PROSITE:PS51181}.
FT   DOMAIN      360    493       C2 tensin-type. {ECO:0000259|PROSITE:
FT                                PS51182}.
FT   ACT_SITE    287    287       Phosphocysteine intermediate.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00160}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFM02299.1}.
FT   NON_TER     493    493       {ECO:0000313|EMBL:KFM02299.1}.
SQ   SEQUENCE   493 AA;  56737 MW;  6941B05CFBDED984 CRC64;
     ASSPTAEEIT VKIDDGRDED NEPDSCSNAI RRKISPFVMS FGFRVFGVVL IVVDIIVVIV
     DLAISEKKKG VREILEGVSL AIALFFLIDV LLRVFVEGFR NYFRSKLNVL DAFIVVGTLL
     INMTYSFSDL AAADQIPRMV TLLRVLRIVI LIRIFRLASQ KKQLEVVTRR MVSENKRRYM
     KDGFDLDLTY VTDRIIAMSF PSSGKQSFYR NPIEEVARFL DTKHADHYKV YNLCSEKGYD
     PKYFHYRVER IFIDDHNVPA LQDMLKFTAS VREWMSQDEK NIIAIHCKGG KGRTGTMVCT
     WLIDSDQFES AKESLDYFGE RRTDRSTSTK FQGVETPSQS RYVGYYEILK NKYNLKLPPE
     RQLKIKNLKI HSIHGVGKGN GTDMKVQIIV RKQVVLECVC ASQGNCKLFF DSESDSVVIG
     LEDSPVISGD VKVRFESHSD LPKGYDDCPF FFWFNTSFIE NNRLYLPRNE LDNPHKSKMW
     KVYTETFAVE VNF
//
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