ID A0A087QQP1_APTFO Unreviewed; 505 AA.
AC A0A087QQP1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Methionine--tRNA ligase, mitochondrial {ECO:0000256|ARBA:ARBA00026124};
DE EC=6.1.1.10 {ECO:0000256|ARBA:ARBA00012838};
DE AltName: Full=Methionyl-tRNA synthetase 2 {ECO:0000256|ARBA:ARBA00029831};
DE AltName: Full=Mitochondrial methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030331};
DE Flags: Fragment;
GN ORFNames=AS27_04357 {ECO:0000313|EMBL:KFM03545.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM03545.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM03545.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM03545.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363039}.
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DR EMBL; KL225814; KFM03545.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087QQP1; -.
DR STRING; 9233.A0A087QQP1; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd07957; Anticodon_Ia_Met; 1.
DR CDD; cd00814; MetRS_core; 1.
DR Gene3D; 2.170.220.10; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041872; Anticodon_Met.
DR InterPro; IPR014758; Met-tRNA_synth.
DR InterPro; IPR023457; Met-tRNA_synth_2.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR033911; MetRS_core.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR NCBIfam; TIGR00398; metG; 1.
DR PANTHER; PTHR43326:SF1; METHIONINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43326; METHIONYL-TRNA SYNTHETASE; 1.
DR Pfam; PF19303; Anticodon_3; 1.
DR Pfam; PF09334; tRNA-synt_1g; 1.
DR PRINTS; PR01041; TRNASYNTHMET.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363039};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363039};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363039};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 1..320
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
FT DOMAIN 354..454
FT /note="Methionyl-tRNA synthetase anticodon-binding"
FT /evidence="ECO:0000259|Pfam:PF19303"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM03545.1"
FT NON_TER 505
FT /evidence="ECO:0000313|EMBL:KFM03545.1"
SQ SEQUENCE 505 AA; 57443 MW; 244414B76642C934 CRC64;
SGTDEHGLKI QQAAAAAGTS PPELCERVSG LFHQALTQAA VSFTDFTRTS EPRHQRAVRH
FWGALRDGGA LYKGSYEGWY CTPEECFLPE SQLAERRDAQ GHPCKVSLET GHQVHWTKEE
NYMFRLSAFR DPLQKWLRDN PHAISPDPFY QHVLRWLEED LPDLSVSRER SRLQWGIPVP
SDSTQTIYVW VDALVNYLSV VGYPETHGEW WPAAHHVVGK DILKFHAVYW PALLMAAGLA
PPERIFVHSH WTVHGQKMSK SLGNVIDPFA CIGRYTVDGF RYFLLRQGVP ERDCDYYDEK
VVKLVNSELA DALGGLLNRS TALSINPSNT YPCFSESCFP KILDYRGTKA VGRASAEDYE
FVASVASLPL QVASYFEGFQ IYKALECIAL CVRQTNSFFQ RHRPWKLNQK DPAEKLWLDT
IIHVTLECLR VYGTLLQPVI PHTADKLLSR LAVEPEERGL SSLTFLPRYN GKPCPFEGRQ
LGPDTGILFQ RLEKSRQHQI ETKKL
//
