ID A0A087QQZ5_APTFO Unreviewed; 956 AA.
AC A0A087QQZ5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=AS27_15555 {ECO:0000313|EMBL:KFM03649.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM03649.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM03649.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM03649.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
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DR EMBL; KL225822; KFM03649.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087QQZ5; -.
DR STRING; 9233.A0A087QQZ5; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd14279; CUE; 1.
DR CDD; cd17998; DEXHc_SMARCAD1; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR003892; CUE.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR PANTHER; PTHR10799:SF964; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51140; CUE; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 94..136
FT /note="CUE"
FT /evidence="ECO:0000259|PROSITE:PS51140"
FT DOMAIN 179..222
FT /note="CUE"
FT /evidence="ECO:0000259|PROSITE:PS51140"
FT DOMAIN 439..607
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 788..950
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 28..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..306
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM03649.1"
FT NON_TER 956
FT /evidence="ECO:0000313|EMBL:KFM03649.1"
SQ SEQUENCE 956 AA; 109575 MW; A99A54209664BDBF CRC64;
STIPETPEAE RTRKRSYLKH RRGVQFLDVS SDSEDEEPRN FSAAKENRAP RRDAVVISEQ
SDDDEQSEDE LPQLAYVNGG DQLPAAKKGV EEDIRDAKLQ TLKELFPQRS DQELLQVIML
SRTMDEAIAA GLKFNDEAAC RKRKLKGSPT NGKNRNEQVT KKPKANYLDE SEPQRQWERQ
EMLVKKLQNT FPGLDKEELR DVLQEHNWVF HEALEALRVF AEDDEGMEFP PKSEASDWTE
ASAKSQSDES KEKPKQKSSG KEQNGFRKKD KGKRSIWNTK RETEDSEDES ASEDGGSSLD
EDYSSGDEVM EDGYKAKILS FLQDASPSEL TLIPQCSQKK AQKIIALRPF NSWEALFTKM
TKTTGLSEDI VWNCKILLKE RDVVLKLMNK CEDISNKLTK QVTRITEDGG CGWNIEQPSI
LNQSLELKPY QKIGLNWLAL LHKHGLNGIL ADEMGLGKTI QAIAFLAYLY QEGNRGPHLI
VVPASTLDNW IREVHLWCPE LNVLFYYGSQ EDRKHLRVDI NNKVVDFNVI VTTYNCAISS
SDDRGLFRRL KLNYAIFDEG HMLKNMSSVR YQHLMTINAK NRLLLTGTPV QNNLLELMSL
LNFVMPHMFS SSTSEIRRMF SSKTKSAEEQ SVYEKERIAH AKQIIKPFIL RRVKDEVLKQ
LPPKKDLIEL CAMSEKQEQL YCDLLNKLKK TIDSNEKNSD MGNVMMQLRK MANHPLLHRQ
YYTTDKLRTM SMLMLKEPTH CDANPDLIFE DMTVMTDFEL HLLCKQYSHV NDFKLDMDQI
LDSGKFRALE RILSDLKEKG DRVVLFSQFT MMLDILEVFL KHWQHRYIRL DGKTQISDRI
HLIDQFNTDM GIFVFLLSTK AGGLGINLTS ANVVILHDID CNPYNDKQAE DRCHRVGQTR
EVKVIKLISK GTIEESMLKI SQQKLKLEQD MTAADSGEEG TIPADIATLL KASLGL
//
