ID A0A087R0C6_APTFO Unreviewed; 614 AA.
AC A0A087R0C6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=E3 SUMO-protein ligase PIAS2 {ECO:0000313|EMBL:KFM06930.1};
DE Flags: Fragment;
GN ORFNames=AS27_03896 {ECO:0000313|EMBL:KFM06930.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM06930.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM06930.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM06930.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR EMBL; KL226008; KFM06930.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087R0C6; -.
DR STRING; 9233.A0A087R0C6; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd16819; SP-RING_PIAS2; 1.
DR Gene3D; 2.60.120.780; PINIT domain; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023321; PINIT.
DR InterPro; IPR038654; PINIT_sf.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF12; E3 SUMO-PROTEIN LIGASE PIAS2; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14324; PINIT; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51466; PINIT; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:KFM06930.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 3..37
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 126..291
FT /note="PINIT"
FT /evidence="ECO:0000259|PROSITE:PS51466"
FT DOMAIN 323..404
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 571..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM06930.1"
FT NON_TER 614
FT /evidence="ECO:0000313|EMBL:KFM06930.1"
SQ SEQUENCE 614 AA; 67360 MW; 57FF06581AD1D4E7 CRC64;
NMVSSFRVSE LQVLLGFAGR NKSGRKHDLL MRALHLLKSG CSPAVQIKIR ELYRRRYPRT
IEGLSDLSAI KPAVFNLDSS SSPVEPDLAV AGIHPLPSTS VTPQSPSSPV SSVLLQDTKP
HFEMQQPSPP IPPVHPDVQL KSLPFYDVLD VLIKPTSLVQ SSIQKFQEKF FIFALTPQQV
REICISRDFL PGGRRDYTVQ VQLRLCLAET SCPQEDNYPN SLCIKVNGKL FPLPGYAPPP
KNGIEQKRPG RPLNITSLVR LSSAVPNQIS ISWASEIGKN YSMSVYLVRQ LTSAMLLQRL
KMKGIRNPDH SRALIKEKLT ADPDSEIATT SLRVSLMCPL GKMRLTIPCR AVTCTHLQCF
DAALYLQMNE KKPTWICPVC DKKAAYESLI LDGLFMEILN ECSDVDEIKF QEDGSWCPMR
PKKEAVKVSS PQCTKIESSS VVSKPCAVTV ANEVNKKKVD VIDLTIESSS DEEEDPPAKR
KCIFMSETQG SPTKGVLMYQ PSTVRVPSVT TVDAAAIPPS LTDYPVPFHH PPISSISSDL
PGLDFLSLIP VDSQYCPPMF LDSLTSTLTS STPGSIITST SHHESSTHVS SSSRSETGVI
TSSGGSAPDI ISLD
//
