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Database: UniProt
Entry: A0A087R628_APTFO
LinkDB: A0A087R628_APTFO
Original site: A0A087R628_APTFO 
ID   A0A087R628_APTFO        Unreviewed;       621 AA.
AC   A0A087R628;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   SubName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 {ECO:0000313|EMBL:KFM08932.1};
DE   Flags: Fragment;
GN   ORFNames=AS27_12795 {ECO:0000313|EMBL:KFM08932.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM08932.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM08932.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM08932.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL226139; KFM08932.1; -; Genomic_DNA.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR030169; K/Na_HCN1.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF373; PTHR10217:SF373; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053286};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00920158, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM      6     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    231    256       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      334    440       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFM08932.1}.
FT   NON_TER     621    621       {ECO:0000313|EMBL:KFM08932.1}.
SQ   SEQUENCE   621 AA;  70980 MW;  1F5791665CD2D778 CRC64;
     RFYWDLIMLI MMVGNLVIIP VGITFFTEQT TTPWIIFNVA SDTVFLLDLI MNFRTGTVNE
     DSSEIILDPK IIKMNYLKSW FVVDFISSIP VDYIFLIVEK GMDSEVYKTA RALRIVRFTK
     ILSLLRLLRL SRLIRYIHQW EEIFHMTYDL ASAVVRIFNL IGMMLLLCHW DGCLQFLVPL
     LQDFPPDCWV SLNGMVNDSW GKQYSYALFK AMSHMLCIGY GARAPVSMSD LWITMLSMIV
     GATCYAMFVG HATALIQSLD SSRRQYQEKY KQVEQYMSFH KLPAEMRQKI HDYYEHRYQG
     KIFDEENILN ELNDPLREEI VNFNCRKLVA TMPLFANADP NFVTAMLSKL RFEVFQPGDY
     IIREGAVGKK MYFIQHGVAG VITKSNKELK LTDGSYFGEI CLLTKGRRTA SVRADTYCRL
     YSLSVDNFNE VLEEYPMMRR AFETVAIDRL DRIGKKNSIL LQKFQKDLNT GVFNNQENEI
     LKQIVKHDRE MVQTIAPVSL QQMPALNSST SASTSRVRTQ SPPVYTASSM SHGNLHSPSP
     STQTPQQAAI LSPCSYTTAV CSPPVQSPLA SRTFQYASPT ASQLSLMQQQ PQVPQQPPGA
     AQKNEVHKST QALHNTNLTR E
//
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