ID   A0A087R7R4_APTFO        Unreviewed;      1196 AA.
AC   A0A087R7R4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Astrotactin-2 {ECO:0000313|EMBL:KFM09518.1};
DE   Flags: Fragment;
GN   ORFNames=AS27_09051 {ECO:0000313|EMBL:KFM09518.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM09518.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM09518.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM09518.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL226182; KFM09518.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087R7R4; -.
DR   STRING; 9233.A0A087R7R4; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001764; P:neuron migration; IEA:InterPro.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR040685; Annexin-like.
DR   InterPro; IPR045574; ASTN1_2_Fn3.
DR   InterPro; IPR045575; ASTN_1_2_N.
DR   InterPro; IPR040510; ASTN_2_hairpin.
DR   InterPro; IPR026995; Astrotactin.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR16592; -; 1.
DR   PANTHER; PTHR16592:SF2; ASTROTACTIN-2; 1.
DR   Pfam; PF18411; Annexin_2; 1.
DR   Pfam; PF19743; ASTN1_2_fn3; 1.
DR   Pfam; PF19441; ASTN_1_2_N; 1.
DR   Pfam; PF18577; ASTN_2_hairpin; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        57..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          712..896
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|SMART:SM00457"
FT   REGION          139..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          219..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..170
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM09518.1"
FT   NON_TER         1196
FT                   /evidence="ECO:0000313|EMBL:KFM09518.1"
SQ   SEQUENCE   1196 AA;  134362 MW;  AC11762028D8BD81 CRC64;
     EMSGTVADIS LVHWKQQWLE NGTLYFHVSM SSAEQLSRAT PPSLQEPSEI VEEQMHILHI
     SVMGGLIALL LLLLVFTVAL YAQRRWHKRR RIPQKSASTE ATHEIHYIPS VLLGPQARES
     FRNSRLQAHN SVIGVPIRET PILDDYEDEE EEETPRRAEP STREDEFGSQ VTRTLESLGR
     GGEEKPDYEK KAPEVTQETV ESLMQKFKES FRTNTPIEIG QLQPALRSTS VGRRKRRSRP
     RGGIGFGRAK GNSGSEADDE TQLTFYTEQY RSRRRSKGSM KSPVNKTALT LIAVSSCVLA
     MVCGSQLSCP LTVKVTLHVP EHFIADGSSF VVSEGSYLDI SDWLNPAKLS LYYQINATSP
     WVRDLCGQRT TDACEQLCDQ ETGLIFPSSL LGECSCHEGY APDPVHRHLC VRSDWGHSEG
     PWPYTTLERG YDLVTGEQAP EKILRSTYSL GQGLWLPVSK SFVVPPVELS INPLASCKTD
     VLVTEDPADV REEAMLSTYF ETINDLLSSF GPVRDCSRNN GGCTRNFKCV SDRKVDSTGC
     VCPEDLRPMK DGTGCYDYSK GIDCSDGFNG GCEQLCLQQT LPLPHDPSSS TIFMFCGCVE
     EYKLAPDGKS CLMLSDICEG PKCLKSDAKF NDTLFGEMLH GYNNRSQHVN QGQVFQMTFR
     ENNFIKDFPQ LADGLMVIPL PVEEQCRGVL SEPLPDLQLL TGDIKYDEAM GYPMVQHWRV
     RSNLYRVKLS SITLSAGFAN ILKILNKDSS REELLSFIQQ FGSHYIAEAL YGSEFSCTIH
     FPSKKVQQQL WLQYQKETTE LGNKKELKSM PFITYLSGLL TAQMLSDDHL ISGVEIHCEE
     KGRCPSTCHL CRRPGKEQLS PTPVLLEINR VVPLYALIQD NDTREAFKGA LMSSYWCSGK
     GDVIEDWCRC DLNAFDENGL PNCSPLPPPV LRLSPNVEPS STVVSLEWLD VQPAIGTKVS
     DYVLQHKKVD EYTDTDLYTG ESLSFADDLL SGLATSCVAA GRSHGDVPET SLYSVIFKCL
     EPDGLYKFTL YAVDTRGRHS ELSTVTLRTA CPLVDDSKAE EIADKIYNLY NGYTSGKEQQ
     TAYNTLMEVS ASMLFRVQHH YNSHYEKFGD FVWRSEDELG PRKAHLILRR LEKVSSHCST
     LLRSAYIQSR TETMPYLFCR SEEVRPPGMV WYSILKDTKV TCEEKMVSML RNTYGE
//