ID A0A087R9E4_APTFO Unreviewed; 2725 AA.
AC A0A087R9E4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Dystrophin {ECO:0000313|EMBL:KFM10098.1};
DE Flags: Fragment;
GN ORFNames=AS27_04961 {ECO:0000313|EMBL:KFM10098.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM10098.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM10098.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM10098.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL226222; KFM10098.1; -; Genomic_DNA.
DR STRING; 9233.A0A087R9E4; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd21233; CH_DMD_rpt2; 1.
DR CDD; cd00176; SPEC; 12.
DR Gene3D; 1.20.58.60; -; 13.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR035436; Dystrophin/utrophin.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF449; -; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00435; Spectrin; 14.
DR PIRSF; PIRSF002341; Dystrophin/utrophin; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00150; SPEC; 18.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 14.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 4..108
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 123..229
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT COILED 736..781
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1532..1566
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1899..1926
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2159..2207
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2485..2529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2564..2618
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM10098.1"
FT NON_TER 2725
FT /evidence="ECO:0000313|EMBL:KFM10098.1"
SQ SEQUENCE 2725 AA; 315455 MW; 308410DCB640CB88 CRC64;
EREDVQKKTF TKWINAQFAK FGRRYIEDLF HDFRDGRRLL ELLECLTGQK LAKEKGSTRV
HALNNVNKAL QVLQRNNVDL VNIGSSDIVD GNHKLTLGLI WNIILHWQVK DVMKNIMAGL
QQTNSEKILL SWVRQSTRNY PQVNVINFTS SWSDGLAFNA LLHSHRPDLF DWNAVASQQS
PVQRLDHAFN IARQHLGIEK LLDPEDIATA CPDKKSIFMY VTSLFQVLPQ QVTMEAIREV
EMLPRHSRVT REEHIQVHHQ QRFTQEITVN VPQGPSSSPK PRFKSYAYTQ AVYVTSPDQK
RRQVPPQFLE TVEEKTFSTM RMGSEMDLEN YQTALEEVLT WLLSAEDALQ AQGDISNDVE
VVKEQFHTHE GFMMELTAHQ GRVGNVLQVG SQLLTIGKLS DDEENEIQEQ MNLLNSRWES
LRVASMEKQS NLHKILMDLQ NQQLAQLAHW LTKTEERTKK IDLEPLGPDL EDLKRQVEEH
KAFQEDLEQE QVKVNSLTHM VVVVDENSGD RATAALEEQL QHFGNRWAAI CRWTEDRWVL
LQDILRKWQQ FAEEQCLFDA WLTEKEDAVS KIHTTGFKDQ NEMLTNLRKL AIIKGDLEVK
RQMMGKLKSL SQDLLVAVKN KAVAQKLESR LENFAQRWDS LVQKVESNSK QISQAVTTTQ
ASLTQTTVME TVTMVTTREQ ILVKHAKEEL PPPPPHKKRQ LLVDSEIRKR FDSDTTELHS
WMTRSEAVLQ SPEFAIYRKE GNLSDLRERV NAIQREKPEK YRKLQDASRS AEALVEQMVN
EGLNADNIRQ ASEQLKSRWI EFCQLLSERL AWLEYQNNII DFYSLLQQLE QTAITAENWL
KVQPTPATDP ATVQTQLEKC KDEIIRMSTL QPQIERLKAQ SQALKEKEQG PVFLDVDLAA
FTSHFKQILA DMQAREKQLQ TIFDSLPPAH YKETMDTILV RIQQSETKLS MPQVVVAEYE
IMEQRLGELK ALQSSLQEQQ KGLNYLSTTV EDMSRKAPAE VSQRYRSEIE VLLGRWKKLS
AQLVEHCQKL EERMTKLQRF QNDTKTLKKW MAEVDVFLKE EWPALGDSEA LEKQLEQCTA
LVNDIQTIQP SLNSVNEIGK KMKSEAEPEF ASRIEIELKD LNVQWEHTCQ QAYAKKAALK
GGLDKTVSLR KDLSEMHEWI TQAEEEYLER DFEYKTPDEL QKAVEELKRA KEEAMQKEVK
VKLITDSVNN FIAKAPPAAH EALKKELDVL ITSYQRLCSR LNGKCKTLEE VWACWRELLS
YLDVENKWLN EIELKLKATE NIQGGAEEIS ESLDSLESLM RHPEDNRSQI RELAQTLTDG
GILDELINEK LEKFNTRWEE LQQEAVRRQK SLEQSIQSAQ ETDKTLRLIQ ESLAVIDKQL
TAYIADRVDA AQVPQEAQKI QSELTSHEIS LEEMKKRNRG KDAAKRVLSQ IDVAQKKLQD
VSMKFRLFQK PANFEQRLQE CKRILDEVKL QVPKLEMKSV EQEVVQSQLD HCMKLYKSLS
EVKSEVETVI KTGRQIVQKQ QTENPKELDE RLTALKLQYN ELGAKVTEKK QELEKCLKLS
RKLRKEINAM TEWLAATDAE LTKRSAVQGM PSNLDAEIAW GKATRKEIEK RHVHLKSISD
LGENLKTVLK GKESLVEDKL SLLNSNWIAV TSRAEEWFNL LLDYQKHMEA FDQNVANVMT
WMYRAEILLD ESDKQKPQQK EEILKRLKAE LKDMHPKVDS VRDQAVDLMT NRGDHCRKII
EPKLSELNQR FATISQRIKS GKPFIPLKEL EQFDFDIQKL LEPLEVEIQQ GVNLKEEDFN
KDTSEDSEST VKELLQRGDT LQKRITDERK REEIKIKQQL LQTKHNALKD LRSQRRKKAL
EISHQWYQYK RQADDLMTWL DDIEKKLASL PDHKDEQKLK EIDGELEKKK EDLNAVHRQA
ERLSKDGAAK AVEPTLIQLS KRWRDFESKF AQFRRLNYAQ IQTVREDTTF VVTETMTVET
THVPSTYLAE ILHLLQALSE VEERLNSPVL QAKDCEDLIK QEECLKSIKD SLGRLLGHID
IIHSKKIRAL QSTTPTEAAN IQEKLTQLNC QWEKVNKMYR DRQVRFDKSL EKWRLFHCDM
KSFNHWLTET EEKLSRAQIE AGDVGHAKTN QFLQELQDGI GRQQTVVKTL NVTGEEIIEQ
SSTADAKALK EQLESLNTRW QEICRQLVEK KKRLEEEKNI LSAFQEDLNK LVLWLEEADS
IIGIPLEPGN EDQLRDCLSK VKLRAEKLPP HKGILKRLNE TGGIALGSAS LNPDKKHKLE
STLKEANHHL LKVSKDLPEK QKEIEILLKD FIELDQQINQ VILWVTPVKN QLELYNKVGQ
PGAFDIKETE AAVQAKQPNV EEVLSKGCHL YKEKPATHPV KKKLEDLNAD WKAINLLIQQ
LKEKPALAAF SLFSSGVLTS GETVAVDTQT RVTKETTTFE PEMPSSVLLE VPALADFNKA
WAELTDWLSR LDREIKSQRV IVGDLDDIND MIIKQKAILQ DLEQRRPQLD ELITAAQNLK
NKTSNQEART IITDRIEKIQ SQWDEVHGHL QSRRQQLHEM LKDSTQWLEA KQEAEQVLEQ
AKAKLESWKE ISYTVEALKK QNTELKQFSK EIRQWQINVD VANDMALKLL RDYSADDTRK
VELMTDNINA TWAAINKRVC EREAALESAL RMLQQFYLDL EKFLAWLTEA ETTANVLQDA
TRKEKLLEDA KTVWDLMKQW QVSQA
//
