ID A0A087RAL2_APTFO Unreviewed; 667 AA.
AC A0A087RAL2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=AS27_11813 {ECO:0000313|EMBL:KFM10516.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM10516.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM10516.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM10516.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL226261; KFM10516.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087RAL2; -.
DR STRING; 9233.A0A087RAL2; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR CDD; cd06659; STKc_PAK6; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR035066; STKc_PAK6.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF19; SERINE_THREONINE-PROTEIN KINASE PAK 6; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00285; PBD; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:KFM10516.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Transferase {ECO:0000313|EMBL:KFM10516.1}.
FT DOMAIN 12..25
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 393..644
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..302
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 422
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 667 AA; 74723 MW; AF70E3999EBC129A CRC64;
MFRKKKKKRP EISAPQNFEH RVHTSFDPKE GKFVGLPPQW QNILDTLRRP KPVVDPSRIT
RMQLQPMKTV VRGSTVEVEG YISGILNDIQ KLSAISSNTL RGRSPTSRRR AQSLGLLGED
RPPDMYLQSP EADWADKYGN YLNCNGGTKV TRRQTMWPDY KPRLEGQSHP NGMVMKAQSL
GPSEFQGADG SCLQRASGLQ HMPTLPGESE KTGKKSSEEC WPQPCLVRQA NSRPSGEGSP
SSKSRENSLK RRLLRSVFPS SSGSNKSGPS LQIKPNAFFR PQQWGSPRSP AAKAQSLPSD
QPASDFPRMI SEAGTPQKSP TAEKAIALPQ GRPSPAGSPR NRQTQTSSSN LHLPQDSSVK
GQLASEDPVV VTHEQFKAAL RMVVDQGDPR TLLENYVKIG EGSTGIVCIA REKHSGRQVA
VKMMDLRKQQ RRELLFNEVV IMRDYQHVNV VEMYKSYLVG EELWVLMEFL QGGALTDIVS
QIRLNEEQIA TVCESVLQAL SYLHSQGVIH RDIKSDSILL TLDGRVKLSD FGFCAQISKD
VPKRKSLVGT PYWMAPEVIA RIPYTTEVDI WSLGIMVIEM VDGEPPYFSD SPVQAMKRLR
DSPPPKLKNF HRTSPVLRDF LERMLTRDPL ERATAQELLD HPFLLQTGLP ECLVPLIQQY
RKRTSTC
//
