ID A0A087RKY6_APTFO Unreviewed; 1829 AA.
AC A0A087RKY6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Laminin subunit alpha-4 {ECO:0000313|EMBL:KFM14140.1};
DE Flags: Fragment;
GN ORFNames=AS27_05570 {ECO:0000313|EMBL:KFM14140.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM14140.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM14140.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM14140.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KL226414; KFM14140.1; -; Genomic_DNA.
DR STRING; 9233.A0A087RKY6; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProt.
DR GO; GO:0005576; C:extracellular region; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF02210; Laminin_G_2; 5.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00282; LamG; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1829
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001828715"
FT DOMAIN 84..133
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 134..188
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 189..242
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 840..1041
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1053..1232
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1239..1407
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1476..1647
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1654..1827
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1418..1455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 441..468
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1431..1446
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 103..112
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 159..168
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 214..223
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 226..240
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1829
FT /evidence="ECO:0000313|EMBL:KFM14140.1"
SQ SEQUENCE 1829 AA; 202879 MW; 1B8F4840F0039693 CRC64;
MALISAWPLV SPILFFLRCF SSSTASSEGG VFQFDIEGSS AVSVQEATVI RGQQQAVATG
SWVPFAEGCQ EGFYRTSLGK CSPCNCNGNA NRCLDGSGIC VDCQRNTTGQ HCEQCPDGFI
GDVVRGVPTF CQPCPCPLPA LANFAVSCYR KSGSVRCVCK ENYAGPNCER CAPGYYGNPL
LIGSTCKKCD CSGNSDPNLI FEDCDEVTGQ CRNCLRNTTG FKCERCAPGY YGDARFAKNC
TECNCGGRMC DSQTGECLAD SPEVSTGTDC PTISCDKCIW DLTDDIRLAV LAIDESKSTL
LSISTGVAAQ KRLNDLNLTA THLQVRTLMT FYFLIQPFTS NTSVNTTLYD KWTFTCLSGE
SKMCGNEASS KGLLVQKETM ETNNRATQLL QQLSNMRDNI EEISSKMKYY AIQQELSPEE
IAQKLSAAEE MLKEIKRRKP FTNQRQLADE EENAAEELVQ QVEEFHKRYN DTRSLVSDVL
EQLSEQDVKL SEVEEALDQA LDYVIQTEDI NKENTANLQR REKQHETIKE QIDEVNGILL
SARTILAGPQ KVNSELSEVI KNVSGFYAEI DGAKKELQEK LANLSLFDDD LVEKAMHHAH
NLRRLADELD RNLYGVDTNG LVQRAINASN VYENIASYIE EANKAALLAL NTTNRVNDAA
VGIDTQIIYH KGKSEELLNR ATELQRTADD SNDLTIADTS RHVNGTLARM NALRSQLTRA
ITKMQSAEPV EARERLEQGK LKTAEAVSAT MTVMQATTPM DENVRLWSQN LQDFQHNSVA
YDSAVHSAGD AVKKLTEVFP QLLDKLRRVE QKAPANNISS SIQRIRELIA QTRSVASKVQ
VSMMFGGQSA VEVNPKINVE ELKSFTSMSL YIKLQKDNPQ LAASPDRFIL YLGNKNAKNY
IGLAIKNDNL VYIYNLGGQD VEIPLDAKPV STWPSYFSII KIERIGRHGK MFLTVPSLSS
TAEEKFIKKG EVLGPGSLLN LEPENTVFYV GGVPPGFTLP PSLNLPGFIG CLELATLNDD
VISLYNFKHV YNIDTTTSPP CARNKLAFTQ SRAVSYFFDG SGYALARNIE RRGRFSQVTR
FDIEVRTPTD NGLILLMING SMFFSLEMHN GFLYLRYDFG FSTGPVLLED SMKKAQINDA
KFHEISIIYH NSKKMILVVD RRHIKSVDNE RTAMPFTDIY IGGAPTEILH SSISSHLAGS
IGFKGCMKGF QFQKKDFNLL EEPGTLGISY GCPEDSLMSR KAYFNGESFI ASSQKVSLFS
EFEGGFNFRT LQPNGLLFYY SEGSDVLSIS MDRGAVVLNA SGTKIQSPDR NYNDGKTHFI
ITSVTPERYE LTVDDKKQSK KNPAKDRAGK SLDSIKKFYF GGSPLRTQQA NFTGCISNAY
FTRLDRDVEV EDFQQYPEKV QTSLYGCPVE SPPVALLHKK GKNSSKAKGN RNKKVGRDKD
KISQTSTGLK KLHQDVNMQR DPQCHLPMNP KATEHAYQFG GTANSRQEFD HIPKDFSERA
QFSISLKTHS SHGMIFYISD QKETNFMALF VAHGRLIFMF NAGHQKIRIK SQEKYNDGLW
HNVIFIRGKN IGRLIIDGLR VLEESFGSNA NTWQVTEPLY IGGVAPGKAV KNIQINSVYS
FSGCLSNLQL NGRSITSASQ TFSVTPCFEG PSEAGTYFSS EGGYVVLDES FSLGLKFEVV
FEIRPRSSSG ILLHGHSVNG EYLNMHMRNG QVTVKLNNGI RDFSTSVTLK QSLCDGRWHR
IAVIRDANVV QLDVDSEVNH VVGPLNPKAT DHREPVFIGG VPESLLTSSL TTRNSFIGCI
RNFMIDEKPV SFSKAALVSG AVSINTCPA
//
