ID A0A087V3R8_BALRE Unreviewed; 976 AA.
AC A0A087V3R8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000313|EMBL:KFO07260.1};
DE Flags: Fragment;
GN ORFNames=N312_07933 {ECO:0000313|EMBL:KFO07260.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO07260.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO07260.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO07260.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL478807; KFO07260.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087V3R8; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24046:SF3; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF07699; Ephrin_rec_like; 2.
DR Pfam; PF14670; FXa_inhibition; 5.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM01411; Ephrin_rec_like; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..41
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 84..120
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 320..358
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 786..898
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 324..334
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO07260.1"
FT NON_TER 976
FT /evidence="ECO:0000313|EMBL:KFO07260.1"
SQ SEQUENCE 976 AA; 108872 MW; F2EC0241DDE8A10C CRC64;
DVDECALGLD DCHPDAICQN TPKLYKCMCK GGYTGEGKKC EDIDECDNDF NGGCVHECFN
IPGNYRCTCY DGFMLAHDGH NCLDTDECMF NNGGCQHVCV NTVGSYECRC KEGFFLSDNQ
HTCIHRSEEG MSCMNKDHGC AHICRETPKG GVACECRPGF ELSKNQRSCI LTCNHGNGGC
QHTCDDADNG PICGCHPKYI MHVDGKTCLE REEAAVEISE GNTTAGADVD KRVKRRLLME
TCAVNNGGCD RTCKDTSTGV HCSCPVGFTL QFDGKTCKDI DECQSNNGGC DHFCKNTVGS
FDCSCRKGFK LLTDEKSCQD IDECSFERTC DHMCINHPGT FECTCNKGYA LYGFTHCGDI
NECSVNNGGC QQLCVNTLGD YECLCHSNYK LHWNKKDCVE TKGPLPDNMS PKVLLHCIKS
GGSDRCFLSC SSDVQVFSGT QDAYTLTCGR SSQLKKKQQN TNASSWLAIK ISVTFKLNEG
KCSLKKTEMF QEGLEQIMSV MESFHYVNLT CSSGKKVHGA ISRLTATREI FITADFELET
SRKEVTDTCD VRCARKKTEK RFRKTIRTLR KTVSRDQFRV RVSGMDHEVA RKSLKLSEPQ
QSCGVGQMHV GNRCGTAANS GTSVQPSQES RAPSCTTVTW EDKSFQMCPP PLLYLPPALF
AEHDIIWCGI SLWSCSPGEY SPDGFKPCLP CPLGTYQPEA GRVSCFPCGG GLTTRHTGGS
LFQDCETKVQ CSPGHFYNTT THRCIRCVVG TYQPEFGQNY CISCPGNTTT DFDGSTNITQ
CKNRQCGGEL GDYTGYIESP NYPGDYPANT ECTWNINPPP KRRILIVVPE IFLPIEDECG
DYLVMRKSSS SNSVTTYETC QTYERPIAFT SRSKKLWIQF KSNEGNSAKG FQVPYVTYDE
DYQELIEDIV RDGRLYASEN HQEILKDKKL IKALFDVLAH PQNYFKYTAQ ESREMFPRSF
IRLLRSKVSR FLRPYK
//
