ID A0A087V4F5_BALRE Unreviewed; 618 AA.
AC A0A087V4F5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Proprotein convertase subtilisin/kexin type 4 {ECO:0000313|EMBL:KFO07497.1};
DE Flags: Fragment;
GN ORFNames=N312_09950 {ECO:0000313|EMBL:KFO07497.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO07497.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO07497.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO07497.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KL479502; KFO07497.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087V4F5; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00064; FU; 1.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.70.850; Peptidase S8, pro-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR032815; S8_pro-domain.
DR InterPro; IPR038466; S8_pro-domain_sf.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR PANTHER; PTHR42884:SF16; PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 4; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16470; S8_pro-domain; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 390..522
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO07497.1"
FT NON_TER 618
FT /evidence="ECO:0000313|EMBL:KFO07497.1"
SQ SEQUENCE 618 AA; 68181 MW; 727190B3747242EF CRC64;
YYHFKHRGTR QKALSTHWGW NMRLTKEPKV LWFEQQTVKR RTKRSVSVVP TDPWFHKQWY
MAASSQAAGR FALPDTRRSA RRLHQAVTTL AERRFAHVCA PFCNRTPWQV MTSTATTPIP
SPGTPPRTRT AHMLTLPLRH GTRCAGEVAA AANNQICGAG IAYNARVGGV RMLDGPITDM
VEAQSLSLRP QHIQIYSASW GPKDDGKTVD RPGVLAAEAF YRGVTKGRGG LGSIFIWASG
NGGINYDNCN CDGYTNSIYT LSVGSVLAGG RRPWYSEGCS TILTTTYSSR TTSEVQIVTT
DLHHRCTDKH TGTSASAPLA AGMIALALEA NPALTWRDLQ HLTVRTSKPA HLQAEDWAVN
GVGRKVSHHY GYGLLDAGLL VEMAKVWTGT QPQRRCSVKA HHPPWNIGSK LTISTDISSC
LGRTKRIRSL EHVQVQLSLS YSRRGDLVIA LTSPMGTTST LVTMRPYDTS QQGYKDWTFM
STHFWDENPN GTWTLQLENK GDAYNTGLLT SFILHLHGTD EDMTARRFAA FAVDKCVRRD
TQGACEECSG SLYAYQRSCL SYCPPRYYGC TQRTAATNTV RVCASCHPSC YTCQGASANS
CTACPPTHTF DKLACSCS
//
