ID A0A087VBR3_BALRE Unreviewed; 616 AA.
AC A0A087VBR3;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Carnitine O-acetyltransferase {ECO:0000313|EMBL:KFO10055.1};
DE Flags: Fragment;
GN ORFNames=N312_06613 {ECO:0000313|EMBL:KFO10055.1};
OS Balearica regulorum gibbericeps (East African grey crowned-crane).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO10055.1, ECO:0000313|Proteomes:UP000053309};
RN [1] {ECO:0000313|EMBL:KFO10055.1, ECO:0000313|Proteomes:UP000053309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO10055.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR EMBL; KL487361; KFO10055.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087VBR3; -.
DR Proteomes; UP000053309; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF50; CARNITINE O-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 28..599
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 333
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
FT BINDING 409
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 413..420
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 442
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 444
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 446
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 455
FT /ligand="(R)-carnitine"
FT /ligand_id="ChEBI:CHEBI:16347"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 494
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT BINDING 545
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO10055.1"
FT NON_TER 616
FT /evidence="ECO:0000313|EMBL:KFO10055.1"
SQ SEQUENCE 616 AA; 70072 MW; 92DBE81F90B46C3C CRC64;
RPYGLLKPTA LGKIPGRFQL HQEALPHLPV PPLQQTLDRY LLALQPIISE EELHHTQELV
AEFRKPGGVG ERLQKGLERR AKKTENWLSD WWLKTAYLEY RLPVVVHSSP GVVLPKQDFL
DRQGQLRFAA RLIEGILDFK AMIDNETLPV EYMGGKPLCM NQYYQILSSC RIPGPKRDSI
VNYAKGKKQS RHITVVHNFQ FFELDVYNSD GSPLTTDQLF IQLEKIWNTS LQTNKEPIGI
LTTNHRNSWA KAYNNLLKDK TNKESVRTIE KSICTVCLDA PMPRVSEDIY KSRVAAQMLH
GGGSRWNSGN RWFDKTLQFI IAEDGSCGLV YEHAPSEGPP IVALLDHIVE YTKRPELVRS
PMIPLPMPKK LRFNITPEIK NDIEKAKQNL NIMVEDLDVK VMVFHQFGKT FPKSEKISPD
AFIQLALQLA YYRMYGHACA TYESASLRMF RLGRTDTIRS TSVDSLKFVQ SMDSPDKSDQ
EKADLLRRAT QAHREYTDMA IRGNAIDRHL LGLKLQAIED LVSMPELFMD TAYAVAMHFN
LSTSQVPAKT DCVMCFGPVV PDGYGICYNP MDEHINFAIS AFNSCADTNA ARMAHYLEKA
LLDMRILLQS TPKSKL
//
