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Database: UniProt
Entry: A0A087VLS1_BALRE
LinkDB: A0A087VLS1_BALRE
Original site: A0A087VLS1_BALRE 
ID   A0A087VLS1_BALRE        Unreviewed;       434 AA.
AC   A0A087VLS1;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   SubName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 {ECO:0000313|EMBL:KFO13563.1};
DE   Flags: Fragment;
GN   ORFNames=N312_02269 {ECO:0000313|EMBL:KFO13563.1};
OS   Balearica regulorum gibbericeps (East African grey crowned-crane).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gruiformes; Gruidae; Balearica.
OX   NCBI_TaxID=100784 {ECO:0000313|EMBL:KFO13563.1, ECO:0000313|Proteomes:UP000053309};
RN   [1] {ECO:0000313|EMBL:KFO13563.1, ECO:0000313|Proteomes:UP000053309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N312 {ECO:0000313|EMBL:KFO13563.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL497915; KFO13563.1; -; Genomic_DNA.
DR   Proteomes; UP000053309; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR030173; HCN4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF375; PTHR10217:SF375; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053309};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00920158, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053309};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM      7     28       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    233    258       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      336    434       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFO13563.1}.
FT   NON_TER     434    434       {ECO:0000313|EMBL:KFO13563.1}.
SQ   SEQUENCE   434 AA;  50642 MW;  C4E76723A0E7F2AA CRC64;
     LSRFYWDLTM LLLMVGNLII IPVGITFFKD ENTTPWIVFN VVSDTFFLID LVLNFRTGIV
     VEDNTEIILD PQRIKMKYLK SWFVVDFISS IPVDYIFLIV ETRIDSEVYK TARALRIVRF
     TKILSLLRLL RLSRLIRYIH QWEEIFHMTY DLASAVVRIV NLIGMMLLLC HWDGCLQFLV
     PMLQDFPDDC WVSLNRMVND SWGKQYSYAL FKAMSHMLCI GYGQQAPVGM SDVWLTMLSM
     IVGATCYAMF IGHATALIQS LDSSRRQYQE KYKQVEQYMS FHKLPADMRQ RIHDYYEHRY
     QGKMFDEESI LGELSEPLRE EIINFNCRKL VASMPLFANA DPNFVTSMLT KLRFEVFQPG
     DYIIREGTIG KKMYFIQHGV VSVLTKGNKE TKLADGSYFG EICLLTRGRR TASVRADTYC
     RLYSLSVDNF NEVL
//
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