ID   A0A087VXC6_ECHMU        Unreviewed;       821 AA.
AC   A0A087VXC6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Pyridoxal dependent decarboxylase {ECO:0000313|EMBL:CDI96935.1};
GN   ORFNames=EmuJ_000066700 {ECO:0000313|EMBL:CDI96935.1};
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211 {ECO:0000313|EMBL:CDI96935.1};
RN   [1] {ECO:0000313|EMBL:CDI96935.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA   Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA   Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA   De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA   Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA   Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA   Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA   Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA   Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA   Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA   Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA   Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA   Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT   "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL   Nature 496:57-63(2013).
RN   [2] {ECO:0000313|EMBL:CDI96935.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; LN902843; CDI96935.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087VXC6; -.
DR   STRING; 6211.A0A087VXC6; -.
DR   eggNOG; KOG0630; Eukaryota.
DR   OMA; KEHEMEN; -.
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR42735; -; 1.
DR   PANTHER; PTHR42735:SF1; PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT   REGION          642..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          781..821
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   821 AA;  91332 MW;  AB5CB9BCAE944299 CRC64;
     MESDMWSLLA ELLTRSVGQS VNSEIEKVRS LIPETGVHLQ NTVNQVDFLL HHLEEKHRQR
     IISRILGDIS VCVEHIWHYS ASCLRVCYGG EDSNESVVTA CRVALQESWY TDTGSPGFSG
     NSPLDSSNSG TASRSVIYLS PAAPSHLRRW LSLNLCCSGL LITVLPAEDN STLPTISVPY
     FERFIQNDLH LGRQPLLLIA YAGSTLTGSS DCLPALARIC RRHKIWLHVE GLSFLRLALL
     TSPPVKPSWM TTINSINLEL SLCFGLPRSL NILLMQSNMP ESILLYLNVF PLTTASEEME
     GATSLPSRSL PSTCLSDALF AWFSLRIQDG SHVNRLRHAD HLTAYTLKKM ESLSSVEIFP
     SHQCLGVTTS NGDRDPDNFF TKMLCENSVH CPLILFRYVL SSSQNVESKL RRKSASVLNA
     KALDEASSKM RFMSESSDAR VDKDQDRPMD QRFLNSLNHW LASALQFEYP NLSIKTHFLS
     NGTLVLRFSL LDCVNLTAIT DRDIDTLVEN ISVNCTIMEA TWWEKPAFCK LIDSTPGLYY
     YHLPDWAGLG AALYVPHTYR CLLPDAGELS PSDYQNHLTT SLLRLPSKAA HDICELNREL
     VSRLRSHDCA FSSARVNLNT VPGVCEALES LASMPVTGQL PSVDSKSSLL NGGEGGNEEG
     RENGVAPISQ MELHCLRFGL ITPGTDTSEM VQMVLRMAKI VEEDSNYVNS LSEVVKRGIE
     EATLHMKEER TKIMREQGVL RQVPYLDKLI NWWSPPVSTQ IHGRMLNLSI GELVPTDSIL
     PVSSPPVARH DQSNEDSAKN EKEPSPSVWS WLLPFSGTST S
//