ID A0A087WP15_MOUSE Unreviewed; 401 AA.
AC A0A087WP15;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Solute carrier organic anion transporter family, member 5A1 {ECO:0000313|Ensembl:ENSMUSP00000139586.2};
GN Name=Slco5a1 {ECO:0000313|Ensembl:ENSMUSP00000139586.2,
GN ECO:0000313|MGI:MGI:2443431};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000139586.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000139586.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139586.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000139586.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139586.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A087WP15; -.
DR SMR; A0A087WP15; -.
DR ProteomicsDB; 347564; -.
DR Antibodypedia; 12199; 49 antibodies from 17 providers.
DR Ensembl; ENSMUST00000146763.8; ENSMUSP00000139586.2; ENSMUSG00000025938.17.
DR UCSC; uc007aih.1; mouse.
DR AGR; MGI:2443431; -.
DR MGI; MGI:2443431; Slco5a1.
DR VEuPathDB; HostDB:ENSMUSG00000025938; -.
DR GeneTree; ENSGT01080000257410; -.
DR HOGENOM; CLU_057532_0_0_1; -.
DR ChiTaRS; Slco5a1; mouse.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000025938; Expressed in lumbar dorsal root ganglion and 134 other cell types or tissues.
DR ExpressionAtlas; A0A087WP15; baseline and differential.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; ISO:MGI.
DR GO; GO:0005886; C:plasma membrane; ISO:MGI.
DR GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0043252; P:sodium-independent organic anion transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF142; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|ProteomicsDB:A0A087WP15};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 43650 MW; 2FD522A2B25B25BC CRC64;
MDEGDAQSRA QQQLEAPSSV GAVQEKCESE SFRSKSLPVL HSASCRQNFS AGNADGKLAL
GCNEAPGRQE THLGRNLIVP SPSAPSTSAG TTTELMDCNH RMDPSKTVSV SSTLATLQER
RCLYVVLTDS RCFLVCMCFL TFIQALMVSG YLSSVITTIE RRYSLKSSES GLLVSCFDIG
NLVVVVFVSY FGGRGRRPLW LAVGGLLIAI GAALFALPHF ISPPYQIQEL NASASNDGLC
QNGNSTAILE PPPCPKDSGG NSHWIYVALF VCAQVLIGMG STPIYTLGPT YLDDNVKKDN
ASLYLAIMYV MGALGPAVGY LLGGLLIGFY VDPRNPVHLD QSDPRFIGNW CHHCPQCRCW
YCPGRLHHKK TEAWCKRICK ASHDLQRGFS AVLLHPVHCW L
//
