ID A0A087X2R9_POEFO Unreviewed; 1168 AA.
AC A0A087X2R9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cell adhesion molecule L1 like {ECO:0000313|Ensembl:ENSPFOP00000000072.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000000072.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000000072.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
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DR EMBL; AYCK01008589; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008592; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008594; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008595; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01008598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007560915.1; XM_007560853.2.
DR AlphaFoldDB; A0A087X2R9; -.
DR STRING; 48698.ENSPFOP00000000072; -.
DR Ensembl; ENSPFOT00000000072.2; ENSPFOP00000000072.2; ENSPFOG00000000052.2.
DR GeneID; 103144064; -.
DR KEGG; pfor:103144064; -.
DR CTD; 100318566; -.
DR eggNOG; KOG3513; Eukaryota.
DR GeneTree; ENSGT00940000165371; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF51; NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 4.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1168
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001832224"
FT TRANSMEM 1046..1067
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..137
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 141..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 256..343
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 348..434
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 440..527
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 531..620
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 631..726
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 731..824
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 829..931
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 933..1032
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 238..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1168 AA; 129693 MW; AA5D60CF24939442 CRC64;
MRSQRSSGLA GRLTLLVVTC LRAFHTTTAI DIPLEVLGHV NIEQLPTITD QAPSSLIAFP
FDESFAMTCE AKGNPEPKFQ WKKNGEDFDP YLDPRLMKEE NSGTFVIPNN GNLTEYQGTY
CCYASNKLGT AISKEIEFIV PNVPKFPKEK LDPVEVEEGQ PFILKCDPPT GIPPLQIYWM
TINLQHIEQD ERVSTGLNGD LYFSHAVEKD SRRDYCCFAA FPRIRTIVQK TAMSVNVKTR
GGDRSESANA ILERKPSLLT PSGGSSENQL VKGEDLELEC IPEGIPTPQV EWIKIGDQLP
VKAKLDNHRK LLIVPRAQQE DSGRYMCRAN NPLGEAVHYF TVTVEGPPEW ESEPQSQLSM
IGSHIHIKCS ARGVPEPTIT WRVNGQLLQD SPVANRKMLS DTIFLQNAKA SDSAVYQCEA
SNRHGTLLSN ANIMIMNLQP MILTNNGEDY SGVEGKGVMM HCKVFSSPPS AITWSRDDSS
ESVAGPRFTL HDNGSLEIHS AEKGDAGQYT CLAKNTEGSS AIDAMLYIKD PTRIVVAPKD
LRILKGSAAQ LSCLAEYDKS FSNDFELLWE KDNIQIALNY TVNPRYIMED GYLNISGVSH
GDQGVYSCVA KTPLDRDTAS AFLMVLDVPV APENLVLSEY KSKSVKLEWI PGDDHNSSPT
EFIIEFEENK WEPGNWKVLL RVPGNHNSAV LRLHGHVEYR FRVYAISAIG AGPPSEPTER
YKTPPSAPDK NPENIKIEGH LPHEMNINWE PLLPIEHNGP GLEYKVSYRR QDGQEEWTEH
TVKRHSFVVR NTPTFVPYEV KIQARNNQGW GPEPRIVSGY SGEDFPSAAP DDVAVEVMNS
SAVRVTWTPV HKDKLHGHLG GYRINWWRLR SLVDSKKSHG DKQSLAFPGD RTHATVPGLT
PFSEYSLIVM TFNGRGNGPG SHPFNFRTPE GVPEKNPVLR VTNVKRNSVS LAWAPPLEPN
GILTGYLLEY QLINDTEEVG PLQAVNISNP NTTKWILHEL EPLTKYKLYL RSCTAVGCGP
VVSEESTTAL ETSLASVHGG ISTQGWFIGL MSAIALLTLI VLIACFVNRN KGGKYSVKEK
EDLHPDVESQ GMNDDTFCEY SDNDEKPLKG SQHSLIREIK VADSGDSLVD YGDEDVQFNE
DGSFIGEYGS CKEKRVSAEV KTSTQIPA
//
