ID A0A087X3P7_POEFO Unreviewed; 548 AA.
AC A0A087X3P7;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Neuropilin (NRP) and tolloid (TLL)-like 2b {ECO:0000313|Ensembl:ENSPFOP00000000400.2};
GN Name=NETO2 {ECO:0000313|Ensembl:ENSPFOP00000000400.2};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000000400.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000000400.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYCK01024546; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A087X3P7; -.
DR STRING; 48698.ENSPFOP00000000400; -.
DR Ensembl; ENSPFOT00000000401.2; ENSPFOP00000000400.2; ENSPFOG00000000358.2.
DR eggNOG; ENOG502QW0Z; Eukaryota.
DR GeneTree; ENSGT00940000156041; -.
DR OMA; KECIYVL; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24251:SF26; NEUROPILIN AND TOLLOID-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..548
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001832246"
FT TRANSMEM 352..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..161
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 180..295
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 446..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 47..74
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 300..312
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 307..325
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 319..334
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 548 AA; 61891 MW; BBF5843611D06C49 CRC64;
YYLSQLCHLL NITWILFFLI EEGFALAQRT KDSPGDPGGQ SPGQNDCGTW VRNINGGVFM
SPNYPNTYPP NKECVYILEA LPRQRIQLAF DKNYYIEPSF QCRFDHIEIR DGPFGFSPII
DRFCGGKNPG LVTSTGRFMW IKFTSDEELE GLGFRIQYTF VADPDFHLHV GGLLNPIPDC
QFEIGGWDGI IRSSQVEEEE RVKPGDALDC IWTIRAPPQS KIYLRFMDYQ MEHSNECKKN
FVAVYDGSSA IENLKAKFCS TVANDLMLDN GVGVIRMWAD EKSRLSRFRM LFTSYIDPPC
TANTFFCHSN MCINNTLVCN GIQNCVYPWD ENHCKEKRSK GLFHQITKTH GTVIGVSSGI
VLVLLIISIL VQMKQPRKKV VARRPGVFNK AGFQEVFDPP HYELFSLRDK EMSSDLGDLS
EELDSFHKVR RSSTMSRCVH EHHCGSQGSV ATGGGGGGGG GSMKHSRTTL SSMELSYHND
FSKPPPMKTF NSTSTYKKSC YGYKQHSQTH DCDQQVIEDR VTEEIPCEIY GRGAVGLDPQ
QRSISMDF
//
