ID   A0A087X839_POEFO        Unreviewed;       760 AA.
AC   A0A087X839;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 2.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000001942.2, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000001942.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01022403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01022404; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A087X839; -.
DR   Ensembl; ENSPFOT00000001946.2; ENSPFOP00000001942.2; ENSPFOG00000002076.2.
DR   GeneTree; ENSGT01100000263513; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          252..386
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          1..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   760 AA;  86694 MW;  608DDE7627956F0D CRC64;
     DLKKDRAEPP GPISPSVRSD RSKDEPPKFS SEPGPSDRKG QNHRGRAEPP GSSCPSMRSD
     RSKRHNPEFS IEPGPSEPEG QNHRGRAEPP GSSCPSMRSD RSKRHNPEFS IEPGPSEPER
     SSCMEEEEQL CARNLNGACR NYSLPLSGTC CSERAWSVSE YVGLQKVLQE HKISLRTRCE
     HVTEGSDETG SRTLLNRIYT DLYITKGQSE DVNTQHEVKQ LERISKIQNL HDYPIRCHDI
     FKTFPDQHGA IRVVLTNGVA GVGKTFSVQK FTLDWGEGFE NQDVSVVVLL SFRELNLIRD
     EQHSLLSLLH VFHPTLQKLP AEQLDNCKLL FIFDGLDESR LSLDFNNSQL VSDVTQKSSV
     NVLLTNLIKG NLLPSALIWI TTRPAAINQV PPSCISRVTE VRGFTDAQKE EYFRKRFNDE
     ELSSRIISHI KKSKTLHIMC AIPIFCWITA TVLENMLTSE QRGELPKTIT DMYSHFLLVQ
     TKRKKNKYHG GHETSPQELM EADRKVLLKL GRLAFEHLEK GNIMFYQEDL EQCGLDVTEA
     LVFSGVCTEI FKRESVIFQK SVYCFVHLSI QEFLAAVYML HCFTSRRSEV IMMFPGEEEE
     DEDKNYNEIS LDEFMNKVMY KSLSSENGHL DLFVRFLHGL TVESNQRLLE DLLGQTENCP
     ETIQSIIINL MEMNTDRISP DRSINIFYCL VEMNDVPFYQ EIKRLLDSGK QQLSVSDCSA
     LAFILQMSEV LDELDLEKYN TSSDGRRRLV PAVRNCRKAR
//