ID A0A087XG15_POEFO Unreviewed; 347 AA.
AC A0A087XG15;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=NIF3-like protein 1 {ECO:0000256|ARBA:ARBA00019069, ECO:0000256|PIRNR:PIRNR037490};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000004718.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000004718.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May function as a transcriptional corepressor through its
CC interaction with COPS2, negatively regulating the expression of genes
CC involved in neuronal differentiation. {ECO:0000256|PIRNR:PIRNR037490}.
CC -!- SUBUNIT: Homodimer. Interacts with COPS2. Interacts with THOC7.
CC {ECO:0000256|PIRNR:PIRNR037490}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR037490}.
CC Nucleus {ECO:0000256|PIRNR:PIRNR037490}.
CC -!- SIMILARITY: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
CC {ECO:0000256|ARBA:ARBA00006964, ECO:0000256|PIRNR:PIRNR037490}.
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DR EMBL; AYCK01014902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007572820.1; XM_007572758.2.
DR RefSeq; XP_007572821.1; XM_007572759.2.
DR AlphaFoldDB; A0A087XG15; -.
DR Ensembl; ENSPFOT00000004727.2; ENSPFOP00000004718.2; ENSPFOG00000004793.2.
DR GeneID; 103152338; -.
DR CTD; 60491; -.
DR GeneTree; ENSGT00390000003590; -.
DR OMA; KYHEFFD; -.
DR OrthoDB; 5490284at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.1390.30; NIF3 (NGG1p interacting factor 3)-like; 2.
DR InterPro; IPR002678; DUF34/NIF3.
DR InterPro; IPR017222; DUF34/NIF3_animal.
DR InterPro; IPR036069; DUF34/NIF3_sf.
DR NCBIfam; TIGR00486; YbgI_SA1388; 1.
DR PANTHER; PTHR13799; NGG1 INTERACTING FACTOR 3; 1.
DR PANTHER; PTHR13799:SF13; NIF3-LIKE PROTEIN 1; 1.
DR Pfam; PF01784; DUF34_NIF3; 1.
DR PIRSF; PIRSF037490; UCP037490_NIF3_euk; 1.
DR SUPFAM; SSF102705; NIF3 (NGG1p interacting factor 3)-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR037490};
KW Nucleus {ECO:0000256|PIRNR:PIRNR037490};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
SQ SEQUENCE 347 AA; 36870 MW; CCAFE37AE50706C1 CRC64;
MELKEVLQVL EQLAPLSLAE SWDNVGLLVE PSKPRPIKTV LLTNDLTDAV MKEAEVLSCD
LIVSYHPPLF RPIKRLAQKD WKQRLAIRAV EAGMAVFSPH TSWDSMKGGV NDWLVGGLGS
GQVSVLSQAH GGASHSHKLE FMVRSPEELN AVVEELKASD DGTALQCSGS RPDSSGIHVS
LTCSASALTP SVQILLKHSA PCQSLSILKL EKAPLPGHGQ GRLSVLDQPV TVATAIQKMK
SHLGLANLRL ALGAGRTLES SVCTAAVCAG SGASVLSSVQ ADLFITGEMS HHEVLDAVAK
GTSVILSDHS NSERGFLAVF RERLAVRLPD AVTVVLSKAD RDPLEVV
//
