ID A0A087XHT6_POEFO Unreviewed; 684 AA.
AC A0A087XHT6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 2.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000005339.2, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000005339.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|ARBA:ARBA00003823,
CC ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; AYCK01007574; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01007575; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007558948.1; XM_007558886.2.
DR AlphaFoldDB; A0A087XHT6; -.
DR STRING; 48698.ENSPFOP00000005339; -.
DR Ensembl; ENSPFOT00000005348.2; ENSPFOP00000005339.2; ENSPFOG00000005262.2.
DR GeneID; 103142716; -.
DR KEGG; pfor:103142716; -.
DR CTD; 55153; -.
DR eggNOG; KOG2229; Eukaryota.
DR GeneTree; ENSGT00390000010355; -.
DR OMA; AMYKTYK; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 62..424
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 486..617
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 636..681
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 484..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..507
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..659
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 79067 MW; EDDD78529D380586 CRC64;
MPGRQSNKLP NNLPQLQNLI KRDPQSYVDE FLQQHRHYQS NVEIFRLQPD KANKDLAELV
MFLSQVAHCY TQQLSTFPRD LSELLRSYHT IIEPELRMTF CKALILLRNK DLIDPTILLE
LFFELLRCHD KLLRKTLYTH IVTDIKNINA KHKNNKINTT LQNFMYTMLR DSNPIAAKIS
LDVMAELYKR NIWNDAKTVN VITTACFSKV TKIIVGGLKF FLGKDEDEKN ESDSESENEG
TSARDLMVKY STGKKNTKNK KKLEKAMKVL KKHKKKKKPE VFNFSAIHLI HDPQDFSEKL
LKQLESSKER FEVKIMMMEL ISRLVGIHEL FLFNFYPFIQ RFLQPHQREV TKILLCAAQA
SHQLVPPEVI EPMIMTIANN FVTDRNSGEV MTVGINAIRE VAGRCPLAIN EDLLQDLAQY
KTHKDKNVMM SARGLIQLFR NLNPQLLHKK DRGRPTEAST EAKIKDYGEL EAKDYIPGAE
VLEVEEENKE EEEDGWESAS ISDDDEDGEW VDVHHSSDED AGEVAEKLQS IPAEERKVKA
AAVSGSWLLT QDDFKKIRLA QMAKEVNAAP GKGQKRKMAD SDNEEDKGEL LTLRHIEKLH
KKPKSDKETR LATAMAGRTD RKEFMKKRTK LNPHASTSNK EKRRKKNFMM MRHSQNVRTK
GKRSFREKQL ALQAALLKKK KQYK
//
